The superoxide dismutase family is composed of three metalloenzymes (SOD-1, SOD-2 and SOD-3) that catalyze the oxido-reduction of reactive oxygen species (ROS) such as superoxide anion. Unlike SOD-1, which is a homodimeric cytosolic Cu-Zn enzyme, SOD-2 is a 22 kDa homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. SOD-1 activity depends on the delivery of copper cofactors by Copper chaperone for SOD-1 (CCS). CCS prevents copper ions from binding to intracellular scavengers, thus securing copper for SOD-1.
Categories
Adenovirus, Over-Expression
Product Type
Pre-Made
Virus Type
Adenovirus
Function
Gene expression
Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Shelf Life
12 Months
HS Code
3822190000
UNSPSC Code
41106621
Insert Gene
SOD1
Availability
Ready to Ship
Titer
1x10^10 PFU/ml
Storage
-80C
Shipping
Dry Ice
Reviews of Superoxide dismutase 1, soluble Adenovirus (Ad-SOD1)