PPARdelta Adenovirus (Ad-PPARd)

Mfr.No.	1284
Description	Peroxisome proliferator-activated receptor delta (PPARd) belongs to the nuclear receptor superfamily, which includes the steroid hormone, thyroid hormone, retinoid, and PPAR subfamilies as well as a growing number of orphan receptors. They function as ligand-dependent sequence-specific activators of transcription. When the PPAR is activated, transcription is increased. However, PPAR can also suppress a number of genes. The function of PPARs depends on the shape of their ligand-binding domain and their co-activators and co-repressors. Ligands for the PPARs include free fatty acids and eicosanoids.Three types of PPARs have been identified: alpha, gamma and delta. PPARd, identical to PPARb, is expressed in many tissues but markedly in brain, adipose tissue and skin. All PPARs dimerize with the retinoid X-receptor (RXR) and bind to PPREs (peroxisome proliferator response elements), which generally occurs in the promoter region of a gene. The GFP tagged to PPARd will allow the determination of the amount and location of PPARd expression. This adenovirus contain PPARdelta with GFP.
Categories	Adenovirus, Over-Expression
Product Type	Pre-Made
Virus Type	Adenovirus
Function	Gene expression
Reporter	eGFP
Storage Buffer	DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone	Human Adenovirus Type5 (dE1/E3)
Shelf Life	12 Months
HS Code	3822190000
UNSPSC Code	41106621
Insert Gene	PPARd
Availability	Ready to Ship
Titer	1x10^10 PFU/ml
Reporter	eGFP
Storage	-80C
Shipping	Dry Ice

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SKU	Supplier No.	Size	Your price	Quantity
BHV21600045	1284	200 µL	$475		Add to Cart