Neuro D (also designated BETA 2) is a basic helix-loop-helix (bHLH) transcription factor functioning in neurogenic differentiation. Neuro D is expressed in pancreatic islet cells and transiently in a subset of neurons in the central and peripheral nervous systems at the time of their terminal differentiation into mature neurons. Moreover, ectopic expression of Neuro D in Xenopus embryos induces premature differentiation of neuronal precursors, and Neuro D can convert presumptive epidermal cells into neurons. BETA 3 is a novel helix-loop-helix protein that can function as a negative regulator of both Neuro D and Myo D-responsive genes. BETA 3 exhibits the highest degree of sequence relatedness with Neuro D and is most highly expressed in lung, kidney and brain cells.
Categories
Adenovirus, Over-Expression
Product Type
Pre-Made
Virus Type
Adenovirus
Function
Gene expression
Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Shelf Life
12 Months
HS Code
3822190000
UNSPSC Code
41106621
Insert Gene
NeuroD1
Availability
Ready to Ship
Titer
1x10^10 PFU/ml
Storage
-80C
Shipping
Dry Ice
Reviews of neurogenic differentiation 1 Adenovirus (Ad-NeuroD1)