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Home / VECTOR &VIRUS / Lentivirus

MEF2 Reporter Lentivirus

SKU : BHV19400063

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Mfr.No.	LTV-0068, LTV-0068-1S, LTV-0068-2S, LTV-0068-3S, LTV-0068-4S, LTV-0068-5S, LTV-0068-6S
Description	MEF2 Reporter Lentivirus: High-quality, lentiviral transcription factor (TF) reporter system that provides a sensitive fluorescent or luminescent readout for human/mouse Myocyte enhancer factor 2 (MEF2) transcription factors in mammalian cells. Vertebrates have at least four versions of the MEF2 gene (MEF2A, MEF2B, MEF2C, and MEF2D), all expressed in distinct but overlapping patterns during embryogenesis through adulthood. MEF2 is a critical regulator of embryonic and heart development. MEF2 affects myocyte differentiation by regulating cardiac gene expression. In adult organisms, MEF2 proteins mediate the stress response in some tissues. The MEF2 Reporter Lentivirus contains tandem repeats of the consensus MEF2 DNA-binding elements to readout transcriptional activity of MEF2 transcription factors (e.g. MEF2A, MEF2B, MEF2C, MEF2D) in mammalian cells. The reporter lentivirus is purified by PEG precipitation and sucrose gradient centrifugation, and is ideal for studying MEF2 activity in difficult-to-transfect cells including primary and/or thawed cells.
Promoter	EF1a
Serotype	VSV-G
Reporter	Firefly Luc, RFP, GFP
Response Element	MEF2 consensus DNA-binding elements
Selection	Blasticidin, Puromycin
Signaling pathway	MEF2 transcription factors
Species	Human/mouse
Applications Range	Monitor transcriptional activity of Myocyte enhancer factor 2 (MEF2) transcription factors (TF) in mammalian cells, screen for activators or inhibitors of MEF2 TFs. The fluorescent reporter enables convenient readout using flow cytometry, fluorescence microscopy, etc. MEF2 is a critical regulator in embryonic and heart development. MEF2 affects myocyte differentiation by regulating cardiac gene expression. In adult organisms, MEF2 proteins mediate the stress response in some tissues. The MEF2 Reporter Lentivirus contains tandem repeats of the consensus MEF2 DNA-binding elements to readout transcriptional activity of MEF2 transcription factors (e.g. MEF2A, MEF2B, MEF2C, MEF2D) in mammalian cells.
Virus Type	TF Reporter Lentivirus

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Combination SKU	Supplier No.	Amount (TU)	Selection	Reporter	Promoter	Your price	Quantity
BHV19400063-1	LTV-0068-1S	5x10^6	Puromycin	GFP	EF1a	$595		Add to Cart
BHV19400063-2	LTV-0068-2S	5x10^6	Blasticidin	RFP	EF1a	$595		Add to Cart
BHV19400063-3	LTV-0068-3S	2x10^6	Puromycin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400063-4	LTV-0068-4S	2x10^6	Blasticidin	Firefly Luc	EF1a	$595		Add to Cart
BHV19400063-5	LTV-0068-5S	5x10^6	Blasticidin	GFP	EF1a	$595		Add to Cart
BHV19400063-6	LTV-0068-6S	5x10^6	Puromycin	RFP	EF1a	$595		Add to Cart

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