MuRF1 (Muscle specific ring finger protein 1) is a nuclear protein that interacts with SMT3b and the large myofibrillar protein titin. MaFbx (Muscle atrophy F-box protein) recognizes and promotes ubiquitination and degradation of phosphorylated proteins during skeletal muscle atrophy. MaFbx or MuRF1 are resistant to atrophy and are therefore potential drug targets for muscle atrophy treatment. Both genes encode ubiquitin ligases and are muscle specific.
Categories
Adenovirus, Over-Expression
Product Type
Pre-Made
Virus Type
Adenovirus
Function
Gene expression
Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Shelf Life
12 Months
HS Code
3822190000
UNSPSC Code
41106621
Insert Gene
Fbox32
Availability
Ready to Ship
Titer
1x10^10 PFU/ml
Storage
-80C
Shipping
Dry Ice
Reviews of F-box only protein 32 Adenovirus (Ad-Fbox32)