Several immediate early response genes are transiently activated in serum- or growth factor-stimulated cells. The early growth response genes encode nuclear proteins Egr-1 (NGFI-A), Egr-2 (Krox20), Egr-3 and Egr-4 (NGFI-C), which contain zinc finger DNA-binding domains closely resembling those of the transcription factor Sp1. The Egr proteins function in transcription regulatory activities surrounding cellular growth, differentiation and function. Wilms¬ø tumor nuclear protein (WT) is an anti-oncogene structurally related to the Egr family.
Categories
Adenovirus, Over-Expression
Product Type
Pre-Made
Virus Type
Adenovirus
Function
Gene expression
Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Shelf Life
12 Months
HS Code
3822190000
UNSPSC Code
41106621
Insert Gene
EGR2
Availability
Ready to Ship
Titer
1x10^10 PFU/ml
Storage
-80C
Shipping
Dry Ice
Reviews of Early growth response 2 (Krox-20 homolog, Drosophila) Adenovirus (Ad-EGR2)