FLIP (FLICE inhibitory protein), also designated CLARP, Casper, I-FLICE, FLAME-1 and MRIT, is expressed as both long (FLIPL) and short (FLIPS) isoforms and is involved in the regulation of apoptosis. The short form of FLIP contains two death effector domains homologous to the death effector domain of the FAS-associating protein FADD. The long form of FLIP contains an additional caspase-like domain, but lacks a catalytic active site and the residues that form the substrate binding pocket in most caspases.
Categories
Adenovirus, Over-Expression
Product Type
Pre-Made
Virus Type
Adenovirus
Function
Gene expression
Promoter
CMV (ubiquitous)
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)
Shelf Life
12 Months
HS Code
3822190000
UNSPSC Code
41106621
Insert Gene
FLIP
Availability
Ready to Ship
Titer
1x10^10 PFU/ml
Storage
-80C
Shipping
Dry Ice
Reviews of CASP8 and FADD-like apoptosis regulator Adenovirus (Ad-FLIP)