(GPRC5D)(G-protein coupled receptor family C group 5 member D)
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80°C. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.
Tag
C-terminal 10xHis-tagged
Molecular Weight
40.6 kDa
Source
Mammalian cell
Endotoxin Level
Less than 1.0 EU/ug as determined by LAL method.
Form
Lyophilized powder
Notes
Repeated freezing and thawing is not recommended. Store the protein at -20°C/-80°C upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity.
Bioactivity
Yes
Expression Region
1-345aa
Lead Time
3-7 business days
Protein Length
Full Length
Uniprot
Q9NZD1
Gene Name
GPRC5D
Function
GPRC5D in MM cells makes this gene and its encoded surface protein as promising markers for monitoring the tumor load and hopefully also as targets for antimyeloma antibodies. PMID: 23510526 Overexpression of G protein-coupled receptor 5D in the bone marrow is associated with poor prognosis in patients with multiple myeloma. PMID: 22591013
Lyophilized from a 0.2 um filtered PBS, 6% Trehalose, pH 7.4
Purity
Testing in progress.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Reviews of Recombinant Human G-protein coupled receptor family C group 5 member D (GPRC5D)-VLPs (Active)