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Home / Proteins & Peptide / Recombinant Protein

Recombinant Human B-lymphocyte antigen CD20(MS4A1)-Detergent (Active)

SKU : BHP10513346

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MP015007HU-D
Alternative Names	(B-lymphocyte surface antigen B1) (Bp35) (Leukocyte surface antigen Leu-16) (Membrane-spanning 4-domains subfamily A member 1) (CD20)
Reconstitution	/
Tag	C-terminal 10xHis-tagged
Molecular Weight	34.4 kDa
Relevance	B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes (PubMed:3925015, PubMed:7684739, PubMed:12920111).<br />Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR (PubMed:7684739, PubMed:12920111, PubMed:18474602).
Source	Mammalian cell
Form	Liquid
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Expression Region	1-297aa
Lead Time	3-7 business days
Protein Length	Full Length

Uniprot	P11836
Gene Name	MS4A1
Research Area	Cancer
Sequence	MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSFFMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKRTCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP

Buffer	50 mM HEPES, 0.15 M NaCl, 0.05% DDM, 0.01% CHS, pH7.5
Purity	Greater than 90% as determined by SDS-PAGE.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. <br />Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Reference	"CD20 homo-oligomers physically associate with the B cell antigen receptor. Dissociation upon receptor engagement and recruitment of phosphoproteins and calmodulin-binding proteins."<br />Polyak M.J., Li H., Shariat N., Deans J.P.<br />J. Biol. Chem. 283:18545-18552(2008)

Product Manual	<a href="https://www.cusabio.com/index.php?m=topdf&c=msds&a=msdsLiquid&id=12936604" target="_blank">MSDS</a>

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SKU	Supplier No.	Size	Your price	Quantity
BHP10513346	CSB-MP015007HU-D	20ug	$855		Add to Cart

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