Atp4b-IRES-CreERT2(2)

Mfr.No.	NM-KI-210119
Description	Model Description: An IRES-CreERT2 expression cassette was knocked into the Atp4b gene stop codon site. Besides,An IRES-CreERT2-WPRE-pA expression cassette were knock into the Atp4b gene start codon site to generate Atp4b-IRES-CreERT2(Stock No. NM-KI-210118) mice. ATP4B could serve as a tumor suppressor in the tumorigenesis and progression. This strain is useful in studying the function of gastric parietal cells in gastric epithelial homeostasis. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cre-expressing cells after tamoxifen treatment. Official Symbol: Atp4b NCBI ID link: 11945 MGI ID link: 88114 Ensembl ID link: ENSMUSG00000031449 Pubmed link: Atp4b Human Ortholog: ATP4B
Nomenclature	C57BL/6JSmoc-Atp4b^{em2(IRES-CreERT2)Smoc}
Strain	Embryo cryopreservation
KI/KO Gene	Atp4b
Synonyms	AV080843

Applications Range	Cre tool mice; stomach
Research Application	Cre/Dre-Driver

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BHAM00487	NM-KI-210119	-		Add to Quote