Ace2-2A-CreERT2

Mfr.No.	NM-KI-200187
Description	Model Description: A 2A-CreERT2-WPRE-polyA expression cassette was knocked into the Ace2 gene stop codon site. Ace2 encodes angiotensin I converting enzyme 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Cre. This strain is useful for studying lung injury and kidney disease caused by SARS coronavirus infection. Official Symbol: Ace2 NCBI ID link: 70008 MGI ID link: 1917258 Ensembl ID link: ENSMUSG00000015405 Pubmed link: Ace2 Human Ortholog: ACE2
Nomenclature	C57BL/6JSmoc-Ace2^{em2(2A-CreERT2-WPRE-polyA)Smoc}
Strain	Embryo cryopreservation
KI/KO Gene	Ace2
Synonyms	2010305L05Rik

Applications Range	Cre recombinase tool
Research Application	Cre/Dre-Driver

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