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Humanized Knockins
Shanghai Model Organisms Center, Inc.
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hTNFSF11/hSIGLEC15
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Cytokines
- KI/KO Gene : TNFSF11
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hTNFRSF1B/hIL2RA
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Embryo cryopres
- Target : Cytokines
- KI/KO Gene : TNFRSF1B
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pCdh16-hENPP3-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Tumor Targets
- KI/KO Gene : Tslp
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pAlb-hAPOB-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Repository Live
- Target : Metabolic Targe
- KI/KO Gene : APOB
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Ighm/Ighd-KO/hSIRPA/hCD47
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Ig
- Strain : Developing
- Target : Metabolic Targe
- KI/KO Gene : SIRPA
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Rag2/IL2rg-KO/hCD40
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Cd
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : CD40
-
hCLDN18.2-Tg
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Tumor Targets
- KI/KO Gene : CD40
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hENTPD1(2)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-En
- Strain : Embryo cryopres
- Target : Cytokine Recept
- KI/KO Gene : Entpd1
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hANGPTL3(5)
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-An
- Strain : Developing
- Target : Cytokine Recept
- KI/KO Gene : Angptl3
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