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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hSERPINH1

    hSERPINH1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Se
    • Strain : Repository Live
    • Target : Other Targets
    • KI/KO Gene : Serpinh1
  • hSIRPA(2)/hCD47/hPD-L1

    hSIRPA(2)/hCD47/hPD-L1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Si
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Cd274
  • hSTING

    hSTING

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tm
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Tmem173
  • hTFRC

    hTFRC

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tf
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Tfrc
  • hTARDBP

    hTARDBP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ta
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Tardbp
  • hSTK25

    hSTK25

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-St
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Stk25
  • hTIM3

    hTIM3

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ha
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Havcr2
  • hTHPO(M-NSG)

    hTHPO(M-NSG)

    • Description : Model Descripti
    • Nomenclature : M-NSG-Thpotm(hT
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Thpo
  • hTLR8/Lyz2-DTREGFP

    hTLR8/Lyz2-DTREGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ly
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : TLR8
  • hTNFRSF13C

    hTNFRSF13C

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Tnfrsf13c
  • hTNFSF13

    hTNFSF13

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Tnfsf13
  • hTNFRSF1B/hPD-1/hPD-L1

    hTNFRSF1B/hPD-1/hPD-L1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Pdcd1
  • hTNFRSF1B/hPD-1

    hTNFRSF1B/hPD-1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Embryo cryopres
    • Target : Cytokine Recept
    • KI/KO Gene : Pdcd1
  • hTSHR(2)

    hTSHR(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ts
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Tshr
  • hTREM2(2)

    hTREM2(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Strain : Repository Live
    • Target : Cytokine Recept
    • KI/KO Gene : Trem2
  • hVSIG4

    hVSIG4

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Vs
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Vsig4
  • hTSLP(M-NSG)

    hTSLP(M-NSG)

    • Description : Model Descripti
    • Nomenclature : M-NSG-Tslptm(hT
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Tslp
  • pAtp4b-hCLDN18.2-Tg

    pAtp4b-hCLDN18.2-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Tslp
  • pAlb-hLPA-Tg

    pAlb-hLPA-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : LPA
  • Rag2/IL2rg-KO/hKDR

    Rag2/IL2rg-KO/hKDR

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : IL2RG
  • R26-LSL-hIL4(M-NSG)

    R26-LSL-hIL4(M-NSG)

    • Description : Model Descripti
    • Nomenclature : NOD-PrkdcscidIl
    • Strain : Developing
    • Target : Metabolic Targe
    • KI/KO Gene : Gt(ROSA)26Sor
  • hTNFSF15(2)

    hTNFSF15(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Developing
    • Target : Metabolic Targe
    • KI/KO Gene : Tnfsf15
  • hVISTA

    hVISTA

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Vs
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Vsir
  • hVEGFA(2)

    hVEGFA(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ve
    • Strain : Repository Live
    • Target : Other Targets
    • KI/KO Gene : Vegfa
  • hTTR(2)

    hTTR(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tt
    • Strain : Repository Live
    • Target : Other Targets
    • KI/KO Gene : Ttr