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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hIL5/hIL5R(3)

    hIL5/hIL5R(3)

    • Strain : Repository Live
    • KI/KO Gene : IL5
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il5
    • Description : The endogenous
  • hIl5

    hIl5

    • Strain : Embryo cryopres
    • KI/KO Gene : IL5
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il5
    • Description : This IL5 humani
  • hLAG3/hCTLA-4

    hLAG3/hCTLA-4

    • Strain : Embryo cryopres
    • KI/KO Gene : CTLA4
    • Research Application : Humanized Drug
    • Nomenclature : B6.129S-Lag3tm1
    • Description : This LAG3 and C
  • hLAG3(BALB/c)

    hLAG3(BALB/c)

    • Strain : Developing
    • KI/KO Gene : Lag3
    • Research Application : Immunotherapy
    • Nomenclature : BALB/cAnSmoc-La
    • Description : The endogenous
  • hMAPT(2)

    hMAPT(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : Mapt
    • Research Application : Alzheimer'S Res
    • Nomenclature : C57BL/6Smoc-Map
    • Description : The endogenous
  • hMAPT

    hMAPT

    • Strain : Repository Live
    • KI/KO Gene : Mapt
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Map
    • Description : The endogenous
  • hLRP5

    hLRP5

    • Strain : Developing
    • KI/KO Gene : Lrp5
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Lrp
    • Description : The endogenous
  • hNR1I2

    hNR1I2

    • Strain : Embryo cryopres
    • KI/KO Gene : Nr1i2
    • Research Application : Pharmacokinetic
    • Nomenclature : C57BL/6Smoc-Nr1
    • Description : The endogenous
  • hNCR3

    hNCR3

    • Strain : Sperm cryoprese
    • KI/KO Gene : Ncr1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Ncr
    • Description : The endogenous
  • hOX40/hOX40L(2)

    hOX40/hOX40L(2)

    • Strain : Embryo cryopres
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tnf
    • Description : hTNFSF4(NM-HU-2
    • Synonyms : Ath1, gp34, Ath
  • hPD-1/hCTLA-4

    hPD-1/hCTLA-4

    • Strain : Embryo cryopres
    • KI/KO Gene : CTLA4
    • Research Application : Cancer Research
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hPD-1(NM-HU-000
  • hPD-1/hCD40

    hPD-1/hCD40

    • Strain : Embryo cryopres
    • KI/KO Gene : CD40
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hPD-1(NM-HU-000
  • hPD-1/hPD-L1(2)/hCCR8

    hPD-1/hPD-L1(2)/hCCR8

    • Strain : Developing
    • KI/KO Gene : CD27
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hPD-1(NM-HU-000
  • hPD-1/hOX40

    hPD-1/hOX40

    • Strain : Embryo cryopres
    • KI/KO Gene : Tnfrsf4
    • Research Application : Cancer Research
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hPD-1(NM-HU-000
  • hCCR8(2)

    hCCR8(2)

    • Strain : Repository Live
    • KI/KO Gene : CCR8
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Ccr
    • Description : The endogenous
  • hCD160

    hCD160

    • Strain : Embryo cryopres
    • KI/KO Gene : Cd160
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Cd1
    • Description : The endogenous
  • hCD27(BALB/c)

    hCD27(BALB/c)

    • Strain : Developing
    • KI/KO Gene : CD27
    • Research Application : Immunotherapy
    • Nomenclature : BALB/cAnSmoc-Cd
    • Description : The endogenous
  • hCD27(2)

    hCD27(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : CD27
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Cd2
    • Description : The endogenous
  • hCD3E/hLAG3

    hCD3E/hLAG3

    • Strain : Embryo cryopres
    • KI/KO Gene : CD3E
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : hCD3E(NM-HU-001
  • hCD38(2)

    hCD38(2)

    • Strain : Repository Live
    • KI/KO Gene : CD38
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : The endogenous
  • hCD3EDG/hCD40/h4-1BB(2)

    hCD3EDG/hCD40/h4-1BB(2)

    • Strain : Developing
    • KI/KO Gene : CD3E
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : hCD3EDG/hCD40(N
  • hCD3EDG/hCD40

    hCD3EDG/hCD40

    • Strain : Developing
    • KI/KO Gene : CD28
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : hCD3EDG(NM-HU-2
  • hCD3EDG/hCD38(2)

    hCD3EDG/hCD38(2)

    • Strain : Developing
    • KI/KO Gene : CD3E
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : hCD3EDG(NM-HU-2
  • hCD3EDG/hCD19

    hCD3EDG/hCD19

    • Strain : Repository Live
    • KI/KO Gene : CD19
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : hCD3EDG(NM-HU-2
  • hCD3EDG/h4-1BB(2)

    hCD3EDG/h4-1BB(2)

    • Strain : Repository Live
    • KI/KO Gene : CD3E
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cd3
    • Description : hCD3EDG(NM-HU-2