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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hCB1(2)

    hCB1(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : Cnr1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Cnr
    • Description : The endogenous
  • hCCR8/hCTLA-4

    hCCR8/hCTLA-4

    • Strain : Embryo cryopres
    • KI/KO Gene : CCR8
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Ccr
    • Description : hCCR8(NM-HU-190
  • hCCR8(BALB/c)

    hCCR8(BALB/c)

    • Strain : Repository Live
    • KI/KO Gene : CCR8
    • Research Application : Immunotherapy
    • Nomenclature : BALB/cAnSmoc-Cc
    • Description : The endogenous
  • hPD-1/hLAG3

    hPD-1/hLAG3

    • Strain : Embryo cryopres
    • KI/KO Gene : LAG3
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hPD-1(NM-HU-000
  • hPD-1/hPD-L1/hTIGIT

    hPD-1/hPD-L1/hTIGIT

    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hTIGIT(NM-HU-00
  • hPD-1/hPD-L1/hLAG3

    hPD-1/hPD-L1/hLAG3

    • Strain : Embryo cryopres
    • KI/KO Gene : LAG3
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hPD-1(NM-HU-000
  • hPD-L1

    hPD-L1

    • Strain : Repository Live
    • KI/KO Gene : Cd274
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Cd2
    • Description : The endogenous
  • hPD-L1/hOX40

    hPD-L1/hOX40

    • Strain : Embryo cryopres
    • KI/KO Gene : Tnfrsf4
    • Research Application : Cancer Research
    • Nomenclature : C57BL/6Smoc-Cd2
    • Description : hPD-L1(NM-HU-00
  • hPD-L1/hVISTA

    hPD-L1/hVISTA

    • Strain : Embryo cryopres
    • KI/KO Gene : Cd274
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Vis
    • Description : hPD-L1(NM-HU-00
  • hPD-L1/hSTING

    hPD-L1/hSTING

    • Strain : Embryo cryopres
    • KI/KO Gene : Cd274
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Tme
    • Description : hPD-L1(NM-HU-00
  • hPD-L1/hSIGLEC15

    hPD-L1/hSIGLEC15

    • Strain : Embryo cryopres
    • KI/KO Gene : Cd274
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Cd2
    • Description : hPD-L1(NM-HU-00
  • hPTGDR2

    hPTGDR2

    • Strain : Sperm cryoprese
    • KI/KO Gene : Ptgdr2
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Ptg
    • Description : The endogenous
  • hSERPINC1

    hSERPINC1

    • Strain : Sperm cryoprese
    • KI/KO Gene : Serpinc1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Ser
    • Description : The endogenous
  • hSDC1

    hSDC1

    • Strain : Embryo cryopres
    • KI/KO Gene : SDC1
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Sdc
    • Description : The endogenous
  • hSIRPA(2)/hCD47/hPD-1

    hSIRPA(2)/hCD47/hPD-1

    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Sir
    • Description : hPD-1(NM-HU-000
  • hSIRPA(2)

    hSIRPA(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : Sirpa
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Sir
    • Description : The endogenous
  • hSIGLEC9

    hSIGLEC9

    • Strain : Repository Live
    • KI/KO Gene : Siglece
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Sig
    • Description : The endogenous
  • hSPN

    hSPN

    • Strain : Repository Live
    • KI/KO Gene : Spn
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Spn
    • Description : The endogenous
  • hSIRPA/hCD47(BALB/c)

    hSIRPA/hCD47(BALB/c)

    • Strain : Repository Live
    • KI/KO Gene : SIRPA
    • Research Application : Tumor Research
    • Nomenclature : BALB/cAnSmoc-Si
    • Description : hCD47 (NM-HU-00
  • hIL2 SP-hIL15-Tg(NMG)

    hIL2 SP-hIL15-Tg(NMG)

    • Strain : Sperm cryoprese
    • KI/KO Gene : Gt(ROSA)26Sor
    • Research Application : Humanized Drug
    • Nomenclature : NOD-PrkdcscidIl
    • Description : These transgeni
  • hIL2RB/hPD-1

    hIL2RB/hPD-1

    • Strain : Repository Live
    • KI/KO Gene : IL2RB
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il2
    • Description : hIL2RB(NM-HU-20
  • hIL2RA/hCCR8

    hIL2RA/hCCR8

    • Strain : Repository Live
    • KI/KO Gene : CCR8
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il2
    • Description : hIL2RA(NM-HU-19
  • hIL33

    hIL33

    • Strain : Repository Live
    • KI/KO Gene : Il33
    • Research Application : Cytokine Humani
    • Nomenclature : C57BL/6Smoc-Il3
    • Description : The endogenous
  • hIL2RG/hIL2RB

    hIL2RG/hIL2RB

    • Strain : Repository Live
    • KI/KO Gene : IL2RB
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il2
    • Description : hIL2RG(NM-HU-20
  • hIL6/hIL6R

    hIL6/hIL6R

    • Strain : Repository Live
    • KI/KO Gene : IL6
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il6
    • Description : This IL6 and IL