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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hTLR8

    hTLR8

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tlr
    • Strain : Repository Live
    • KI/KO Gene : TLR8
    • Research Application : Immunotherapy
  • hTNFa-Tg

    hTNFa-Tg

    • Description : These transgeni
    • Nomenclature : C57BL/6Smoc-Tgt
    • Strain : Repository Live
    • KI/KO Gene : TLR8
    • Synonyms : DIF,TNFA,TNFSF2
  • hTPBG

    hTPBG

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tpb
    • Strain : Repository Live
    • KI/KO Gene : Tpbg
    • Synonyms : 5T4; WAIF1; AW4
  • hTP53(2)

    hTP53(2)

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Trp
    • Strain : Repository Live
    • KI/KO Gene : Trp53
    • Synonyms : bbl; bfy; bhy;
  • hIL2/hIL2RB/hIL2RG

    hIL2/hIL2RB/hIL2RG

    • Description : hIL2RG(NM-HU-20
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Repository Live
    • KI/KO Gene : IL2
    • Synonyms : Il-2
  • hIL2/hIL2RA

    hIL2/hIL2RA

    • Description : hIL2(NM-HU-1900
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Repository Live
    • KI/KO Gene : IL2
    • Synonyms : Il-2,I, CD25, I
  • hIL2RG

    hIL2RG

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Embryo cryopres
    • KI/KO Gene : IL2RG
    • Synonyms : gc; p64; (g)c
  • hIL2RA/hIL2RB/hIL2RG

    hIL2RA/hIL2RB/hIL2RG

    • Description : hIL2RA(NM-HU-19
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Repository Live
    • KI/KO Gene : IL2RA
    • Synonyms : CD25; Il2r; I
  • hIL2RA

    hIL2RA

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Repository Live
    • KI/KO Gene : IL2RA
    • Synonyms : CD25; Il2r; I
  • hIL3/hCSF2/hSIRPA(2)/hCD47

    • Description : hIL3(NM-HU-1900
    • Nomenclature : C57BL/6Smoc-Il3
    • Strain : Repository Live
    • KI/KO Gene : IL3
    • Synonyms : BPA; PSF; HCG
  • hIL4/hIL4R

    hIL4/hIL4R

    • Description : These mice are
    • Nomenclature : C57BL/6Smoc-Il4
    • Strain : Repository Live
    • KI/KO Gene : IL4
    • Synonyms : Il-4; BSF-1
  • hITGAV

    hITGAV

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Itg
    • Strain : Embryo cryopres
    • KI/KO Gene : Itgav
    • Synonyms : CD51; 1110004F1
  • hIL7(BALB/c)

    hIL7(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Il
    • Strain : Repository Live
    • KI/KO Gene : Il7r
    • Synonyms : CD127; IL-7Ralp
  • hIL6ST

    hIL6ST

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il6
    • Strain : Embryo cryopres
    • KI/KO Gene : Il6st
    • Synonyms : CD130, gp130, A
  • hLILRB2-hLILRB3-Tg

    hLILRB2-hLILRB3-Tg

    • Description : These transgeni
    • Nomenclature : C57BL/6Smoc-Tg(
    • Strain : Repository Live
    • KI/KO Gene : LILRB2
    • Synonyms : ILT4; LIR2; CD8
  • hLAIR1

    hLAIR1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Lai
    • Strain : Embryo cryopres
    • KI/KO Gene : Lair1
    • Synonyms : Lair-1, BB11526
  • hMERTK

    hMERTK

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Mer
    • Strain : Embryo cryopres
    • KI/KO Gene : Mertk
    • Synonyms : Eyk; Mer; Nyk;
  • hMARCO

    hMARCO

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Mar
    • Strain : Embryo cryopres
    • KI/KO Gene : Marco
    • Synonyms : Ly112; Scara2;
  • hLYPD3

    hLYPD3

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Lyp
    • Strain : Embryo cryopres
    • KI/KO Gene : Lypd3
    • Synonyms : C4.4a, 2310061G
  • hLILRB4

    hLILRB4

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Lil
    • Strain : Embryo cryopres
    • KI/KO Gene : Lypd3
    • Synonyms : IL, Li, HM18, I
  • hMIF

    hMIF

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Mif
    • Strain : Embryo cryopres
    • KI/KO Gene : Mif
    • Synonyms : GIF, DER6, Glif
  • hOX40/Cd8a-IRES-Luc-2A-EGFP

    • Description : hOX40(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Embryo cryopres
    • KI/KO Gene : Tnfrsf4
    • Synonyms : Ox40; ACT35;
  • hPD-1(BALB/c)

    hPD-1(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Pd
    • Strain : Repository Live
    • KI/KO Gene : Tnfrsf4
    • Synonyms : PD-1 Pdc1 Ly101
  • hPD-1/hPD-L1

    hPD-1/hPD-L1

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Repository Live
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-1/hLAG3/hTIGIT

    hPD-1/hLAG3/hTIGIT

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : LAG3
    • Synonyms : Ly66; CD223;