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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hIL3/hCSF2/hCSF1

    hIL3/hCSF2/hCSF1

    • Strain : Embryo cryopres
    • KI/KO Gene : CSF1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il3
    • Description : hIL3(NM-HU-1900
  • hIL3

    hIL3

    • Strain : Embryo cryopres
    • KI/KO Gene : IL3
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il3
    • Description : The endogenous
  • hIL5-Tg(NMG,2)

    hIL5-Tg(NMG,2)

    • Strain : Sperm cryoprese
    • KI/KO Gene : Gt(ROSA)26Sor
    • Research Application : Humanized Drug
    • Nomenclature : NOD-PrkdcscidIl
    • Description : These transgeni
  • hIL4RA

    hIL4RA

    • Strain : Embryo cryopres
    • KI/KO Gene : Il4ra
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Il4
    • Description : The endogenous
  • hIL4/hIL4R(BALB/c)

    hIL4/hIL4R(BALB/c)

    • Strain : Repository Live
    • KI/KO Gene : IL4
    • Research Application : Humanized Drug
    • Nomenclature : BALB/cAnSmoc-Il
    • Description : The endogenous
  • hIL9(BALB/c)

    hIL9(BALB/c)

    • Strain : Repository Live
    • KI/KO Gene : Il9
    • Research Application : Humanized Drug
    • Nomenclature : BALB/cAnSmoc-Il
    • Description : The endogenous
  • hIL7

    hIL7

    • Strain : Embryo cryopres
    • KI/KO Gene : Il7
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Il7
    • Description : The endogenous
  • hLAIR1/hPD-1/hPD-L1

    hLAIR1/hPD-1/hPD-L1

    • Strain : Embryo cryopres
    • KI/KO Gene : LAIR1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Lai
    • Description : hLAIR1(NM-HU-20
  • hLAG3

    hLAG3

    • Strain : Repository Live
    • KI/KO Gene : LAG3
    • Research Application : Immunotherapy
    • Nomenclature : B6.129S-Lag3tm1
    • Description : The endogenous
  • hKLRK1

    hKLRK1

    • Strain : Embryo cryopres
    • KI/KO Gene : Klrk1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Klr
    • Description : The endogenous
  • hLY96

    hLY96

    • Strain : Embryo cryopres
    • KI/KO Gene : Ly96
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Ly9
    • Description : The endogenous
  • hNR3C1

    hNR3C1

    • Strain : Sperm cryoprese
    • KI/KO Gene : Nr3c1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Nr3
    • Description : The endogenous
  • hNCR2

    hNCR2

    • Strain : Sperm cryoprese
    • KI/KO Gene : Ncr1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Ncr
    • Description : The endogenous
  • hMIEN1

    hMIEN1

    • Strain : Embryo cryopres
    • KI/KO Gene : Mien1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Mie
    • Description : The endogenous
  • hOX40(2)

    hOX40(2)

    • Strain : Repository Live
    • KI/KO Gene : Tnfrsf4
    • Research Application : Cancer Research
    • Nomenclature : C57BL/6Smoc-Tnf
    • Description : The exon1-5 and
  • hOX40

    hOX40

    • Strain : Repository Live
    • KI/KO Gene : Tnfrsf4
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Tnf
    • Description : The endogenous
  • hPD-1/hICOS(2)

    hPD-1/hICOS(2)

    • Strain : Embryo cryopres
    • KI/KO Gene : ICOS
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hPD-1(NM-HU-000
  • hPD-1/hCD3E

    hPD-1/hCD3E

    • Strain : Embryo cryopres
    • KI/KO Gene : CD3E
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hPD-1(NM-HU-000
  • hPD-1/hCD28

    hPD-1/hCD28

    • Strain : Repository Live
    • KI/KO Gene : CD28
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hPD-1(NM-HU-000
  • hPD-1/Cd8a-IRES-Akaluc-2A-EGFP

    • Strain : Embryo cryopres
    • KI/KO Gene : Mst1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hPD-1(NM-HU-000
  • hPD-1/hPD-L1/hCTLA-4

    hPD-1/hPD-L1/hCTLA-4

    • Strain : Embryo cryopres
    • KI/KO Gene : CTLA4
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : hCTLA4(NM-HU-00
  • hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c)

    • Strain : Developing
    • KI/KO Gene : Pdcd1
    • Research Application : Humanized Drug
    • Nomenclature : BALB/cAnSmoc-Pd
    • Description : hSIRPA/hCD47(BA
  • hPD-1/hPD-L1(BALB/c)

    hPD-1/hPD-L1(BALB/c)

    • Strain : Repository Live
    • KI/KO Gene : Pdcd1
    • Research Application : Humanized Drug
    • Nomenclature : BALB/cAnSmoc-Pd
    • Description : hPD-1(BALB/c)(N
  • hTIGIT

    hTIGIT

    • Strain : Repository Live
    • KI/KO Gene : TIGIT
    • Research Application : Immunotherapy
    • Nomenclature : C57BL/6Smoc-Tig
    • Description : The endogenous
  • hTLR8/hPD-1

    hTLR8/hPD-1

    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Research Application : Humanized Drug
    • Nomenclature : C57BL/6Smoc-Tlr
    • Description : hTLR8(NM-HU-190