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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hIL17RA(BALB/c)

    hIL17RA(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Il
    • Strain : Repository Live
    • KI/KO Gene : IL17RA
    • Synonyms : Il17r; Cdw217
  • hPD-1/hSIGLEC15

    hPD-1/hSIGLEC15

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-1/hPD-L1/hPD-L2

    hPD-1/hPD-L1/hPD-L2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-L1(2)/hCCR8

    hPD-L1(2)/hCCR8

    • Description : hPD-1(2)(NM-HU-
    • Nomenclature : C57BL/6Smoc-Cd2
    • Strain : Embryo cryopres
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P
  • hPD-1/hVISTA

    hPD-1/hVISTA

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Vis
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-1/hTLR9

    hPD-1/hTLR9

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-L1/hSEMA4D

    hPD-L1/hSEMA4D

    • Description : hPD-L1(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Cd2
    • Strain : Embryo cryopres
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P
  • hPD-L1/h4-1BB(2)

    hPD-L1/h4-1BB(2)

    • Description : hPD-L1(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Cd2
    • Strain : Embryo cryopres
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P
  • hPD-L1(BALB/c)

    hPD-L1(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Cd
    • Strain : Repository Live
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P
  • hPD-L1/hTIGIT

    hPD-L1/hTIGIT

    • Description : hPD-L1(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Cd2
    • Strain : Repository Live
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P
  • hSIGLEC10

    hSIGLEC10

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Sig
    • Strain : Repository Live
    • KI/KO Gene : Siglecg
    • Synonyms : Siglec-G; Sigl
  • hSERPINH1

    hSERPINH1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ser
    • Strain : Sperm cryoprese
    • KI/KO Gene : Serpinh1
    • Synonyms : J6; Cbp1; Cbp2;
  • hRSPO1

    hRSPO1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Rsp
    • Strain : Sperm cryoprese
    • KI/KO Gene : Rspo1
    • Synonyms : Rspondin; R-spo
  • hSOST

    hSOST

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Sos
    • Strain : Repository Live
    • KI/KO Gene : Sost
    • Synonyms : 5430411E23Rik
  • hSOD1

    hSOD1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Sod
    • Strain : Repository Live
    • KI/KO Gene : Sod1
    • Synonyms : Ipo1; SODC; Ipo
  • hTIGIT/hPVR

    hTIGIT/hPVR

    • Description : These mice are
    • Nomenclature : C57BL/6Smoc-Tig
    • Strain : Embryo cryopres
    • KI/KO Gene : TIGIT
    • Synonyms : Vstm3
  • hCCR5

    hCCR5

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ccr
    • Strain : Embryo cryopres
    • KI/KO Gene : Ccr5
    • Synonyms : AM4-7; CD195; C
  • hCD24

    hCD24

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Cd2
    • Strain : Repository Live
    • KI/KO Gene : CD24a
    • Synonyms : HSA; Cd24; Ly
  • hCD19/hCD3E

    hCD19/hCD3E

    • Description : This CD19 and C
    • Nomenclature : C57BL/6Smoc-Cd1
    • Strain : Embryo cryopres
    • KI/KO Gene : CD19
    • Synonyms : AW495831
  • hCD147

    hCD147

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Bsg
    • Strain : Repository Live
    • KI/KO Gene : Bsg
    • Synonyms : HT-7; CD147; EM
  • hCD37

    hCD37

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Cd3
    • Strain : Embryo cryopres
    • KI/KO Gene : Cd37
    • Synonyms : Tspan26
  • hCD3E/hCD28

    hCD3E/hCD28

    • Description : hCD3E(NM-HU-001
    • Nomenclature : C57BL/6Smoc-Cd3
    • Strain : Embryo cryopres
    • KI/KO Gene : CD28
    • Synonyms : Tspan26
  • hCD3EDG/hCD20(2)

    hCD3EDG/hCD20(2)

    • Description : hCD3EDG(NM-HU-2
    • Nomenclature : C57BL/6Smoc-Cd3
    • Strain : Embryo cryopres
    • KI/KO Gene : CD3E
    • Synonyms : CD3; T3e; AI5
  • hCD3EDG

    hCD3EDG

    • Description : The endogenous
    • Nomenclature : C57BL/6-Cd3etm1
    • Strain : Repository Live
    • KI/KO Gene : CD3E
    • Synonyms : CD3; T3e; AI5
  • hCD40/h4-1BB(2)

    hCD40/h4-1BB(2)

    • Description : hCD40(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Cd4
    • Strain : Repository Live
    • KI/KO Gene : CD40
    • Synonyms : IGM; p50; Bp5