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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hPD-1/hIL1B

    hPD-1/hIL1B

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-1/hSEMA4D

    hPD-1/hSEMA4D

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-1/hPD-L1/hOX40

    hPD-1/hPD-L1/hOX40

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Embryo cryopres
    • KI/KO Gene : Tnfrsf4
    • Synonyms : Ox40; ACT35;
  • hPD-1/hVEGFR2

    hPD-1/hVEGFR2

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-1/hTIM3

    hPD-1/hTIM3

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-L1/hCTLA-4

    hPD-L1/hCTLA-4

    • Description : hPD-L1(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Ctl
    • Strain : Embryo cryopres
    • KI/KO Gene : CTLA4
    • Synonyms : Cd152; Ly-56;
  • hPD-L1/hCD73(2)

    hPD-L1/hCD73(2)

    • Description : hPD-L1(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Cd2
    • Strain : Embryo cryopres
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P
  • hPD-L1/hCD28

    hPD-L1/hCD28

    • Description : hPD-L1(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Cd2
    • Strain : Repository Live
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P
  • hPD-L2(BALB/c)

    hPD-L2(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Pd
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1lg2
    • Synonyms : Btdc; B7-DC;
  • hPD-L1/hSIRPA(2)

    hPD-L1/hSIRPA(2)

    • Description : hPD-L1(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Sir
    • Strain : Embryo cryopres
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P
  • hPVRL2

    hPVRL2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Nec
    • Strain : Repository Live
    • KI/KO Gene : Nectin2
    • Synonyms : MPH; Pvr; Pvs;
  • hPVRIG

    hPVRIG

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Pvr
    • Strain : Repository Live
    • KI/KO Gene : Pvrig
    • Synonyms : Gm36869
  • hPVR

    hPVR

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Pvr
    • Strain : Embryo cryopres
    • KI/KO Gene : Pvr
    • Synonyms : PVS, mE4, HVED,
  • hPTPRC

    hPTPRC

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ptp
    • Strain : Repository Live
    • KI/KO Gene : Ptprc
    • Synonyms : loc,B220,Cd45,L
  • hPSMA

    hPSMA

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Fol
    • Strain : Repository Live
    • KI/KO Gene : Folh1
    • Synonyms : GCP2; mopsm
  • hSIGLEC15(BALB/c)

    hSIGLEC15(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Si
    • Strain : Repository Live
    • KI/KO Gene : SIGLEC15
    • Synonyms : Cd33l3; EG6202
  • hSIGLEC15

    hSIGLEC15

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Sig
    • Strain : Repository Live
    • KI/KO Gene : SIGLEC15
    • Synonyms : Cd33l3; EG6202
  • hSERPINA1

    hSERPINA1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ser
    • Strain : Repository Live
    • KI/KO Gene : Serpina1e
    • Synonyms : PI5,Dom5,Spi1-5
  • hSIRPA(BALB/c,2)

    hSIRPA(BALB/c,2)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Si
    • Strain : Embryo cryopres
    • KI/KO Gene : IL11
    • Synonyms : IL-11
  • hSIRPA(2)/hCD47/hPD-1/hPD-L1

    • Description : hSIRPA(2)(NM-HU
    • Nomenclature : C57BL/6Smoc-Sir
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hSIGLEC8(2)

    hSIGLEC8(2)

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Sig
    • Strain : Embryo cryopres
    • KI/KO Gene : Siglecf
    • Synonyms : Siglec5; mSigle
  • hSTING

    hSTING

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tme
    • Strain : Repository Live
    • KI/KO Gene : Tmem173
    • Synonyms : ERIS; MPYS; M
  • hSOST(2)

    hSOST(2)

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Sos
    • Strain : Repository Live
    • KI/KO Gene : Sost
    • Synonyms : 5430411E23Rik
  • hTIGIT(BALB/c,2)

    hTIGIT(BALB/c,2)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Ti
    • Strain : Repository Live
    • KI/KO Gene : Tigit
    • Synonyms : Vstm3
  • hIL18R1

    hIL18R1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Developing
    • KI/KO Gene : Il18r1
    • Synonyms : Il1rrp; Il18ral