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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hIL9(BALB/c)

    hIL9(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Il
    • Strain : Repository Live
    • KI/KO Gene : Il9
    • Synonyms : P40; Il-9
  • hIL7

    hIL7

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il7
    • Strain : Embryo cryopres
    • KI/KO Gene : Il7
    • Synonyms : Il-7, hlb368, A
  • hLAIR1/hPD-1/hPD-L1

    hLAIR1/hPD-1/hPD-L1

    • Description : hLAIR1(NM-HU-20
    • Nomenclature : C57BL/6Smoc-Lai
    • Strain : Embryo cryopres
    • KI/KO Gene : LAIR1
    • Synonyms : Lair-1; BB1152
  • hLAG3

    hLAG3

    • Description : The endogenous
    • Nomenclature : B6.129S-Lag3tm1
    • Strain : Repository Live
    • KI/KO Gene : LAG3
    • Synonyms : Ly66; CD223;
  • hKLRK1

    hKLRK1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Klr
    • Strain : Embryo cryopres
    • KI/KO Gene : Klrk1
    • Synonyms : Nkg2d, NKG2-D,
  • hLY96

    hLY96

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ly9
    • Strain : Embryo cryopres
    • KI/KO Gene : Ly96
    • Synonyms : MD2; MD-2; ESOP
  • hNR3C1

    hNR3C1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Nr3
    • Strain : Sperm cryoprese
    • KI/KO Gene : Nr3c1
    • Synonyms : GR; Grl1; Grl-1
  • hNCR2

    hNCR2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ncr
    • Strain : Sperm cryoprese
    • KI/KO Gene : Ncr1
    • Synonyms : Ly94,NKp46
  • hMIEN1

    hMIEN1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Mie
    • Strain : Embryo cryopres
    • KI/KO Gene : Mien1
    • Synonyms : Rdx12, AI463380
  • hOX40(2)

    hOX40(2)

    • Description : The exon1-5 and
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Repository Live
    • KI/KO Gene : Tnfrsf4
    • Synonyms : Ox40; ACT35;
  • hOX40

    hOX40

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Repository Live
    • KI/KO Gene : Tnfrsf4
    • Synonyms : Ox40; ACT35;
  • hPD-1/hICOS(2)

    hPD-1/hICOS(2)

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : ICOS
    • Synonyms : AILIM; CCLP;
  • hPD-1/hCD3E

    hPD-1/hCD3E

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : CD3E
    • Synonyms : CD3; T3e; AI5
  • hPD-1/hCD28

    hPD-1/hCD28

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Repository Live
    • KI/KO Gene : CD28
    • Synonyms : CD3; T3e; AI5
  • hPD-1/Cd8a-IRES-Akaluc-2A-EGFP

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Mst1
    • Synonyms : Hgfl; D3F15S2h
  • hPD-1/hPD-L1/hCTLA-4

    hPD-1/hPD-L1/hCTLA-4

    • Description : hCTLA4(NM-HU-00
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : CTLA4
    • Synonyms : Cd152; Ly-56;
  • hPD-1/hPD-L1/hCD47/hSIRPA(BALB/c)

    • Description : hSIRPA/hCD47(BA
    • Nomenclature : BALB/cAnSmoc-Pd
    • Strain : Developing
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-1/hPD-L1(BALB/c)

    hPD-1/hPD-L1(BALB/c)

    • Description : hPD-1(BALB/c)(N
    • Nomenclature : BALB/cAnSmoc-Pd
    • Strain : Repository Live
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hTIGIT

    hTIGIT

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tig
    • Strain : Repository Live
    • KI/KO Gene : TIGIT
    • Synonyms : Vstm3
  • hTLR8/hPD-1

    hTLR8/hPD-1

    • Description : hTLR8(NM-HU-190
    • Nomenclature : C57BL/6Smoc-Tlr
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hTNFRSF1A

    hTNFRSF1A

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Embryo cryopres
    • KI/KO Gene : Sost
    • Synonyms : 5430411E23Rik
  • hTNFR2/hIL2RA

    hTNFR2/hIL2RA

    • Description : hTNFRSF1B(NM-HU
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Embryo cryopres
    • KI/KO Gene : IL2RA
    • Synonyms : CD25; Il2r; I
  • hTTR

    hTTR

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ttr
    • Strain : Sperm cryoprese
    • KI/KO Gene : Ttr
    • Synonyms : D17860; AA40876
  • hTREM2

    hTREM2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tre
    • Strain : Repository Live
    • KI/KO Gene : Trem2
    • Synonyms : TREM-2; Trem2a;
  • hVISTA

    hVISTA

    • Description : The exon 2-3 of
    • Nomenclature : C57BL/6Smoc-Vsi
    • Strain : Embryo cryopres
    • KI/KO Gene : Vsir
    • Synonyms : Dies1; PD-1H;