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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hF12

    hF12

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-F12
    • Strain : Repository Live
    • KI/KO Gene : F12
    • Synonyms : HAF; FXII
  • hF11

    hF11

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-F11
    • Strain : Repository Live
    • KI/KO Gene : F11
    • Synonyms : FXI; PTA; Cf11;
  • hACE2

    hACE2

    • Description : A human ACE2-fl
    • Nomenclature : C57BL/6Smoc-Ace
    • Strain : Repository Live
    • KI/KO Gene : ACE2
    • Synonyms : ACEH
  • h4-1BB(2)/hPD-1

    h4-1BB(2)/hPD-1

    • Description : h4-1BB(2)(NM-HU
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Repository Live
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • h4-1BB(2)/hCD3E(2)

    h4-1BB(2)/hCD3E(2)

    • Description : h4-1BB(2)(NM-HU
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Repository Live
    • KI/KO Gene : CD3E
    • Synonyms : CD3; T3e; AI5
  • hANGPT2

    hANGPT2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ang
    • Strain : Developing
    • KI/KO Gene : Angpt2
    • Synonyms : Ang2, Agpt2, An
  • hB7H4

    hB7H4

    • Description : This VTCN1 huma
    • Nomenclature : C57BL/6Smoc-Vtc
    • Strain : Embryo cryopres
    • KI/KO Gene : Vtcn1
    • Synonyms : B7-H4 B7x
  • hB7H3

    hB7H3

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Cd2
    • Strain : Embryo cryopres
    • KI/KO Gene : CD276
    • Synonyms : B7H3; B7-h3; B
  • hB2M-HLA A2.1(NMG,2)

    hB2M-HLA A2.1(NMG,2)

    • Description : The endogenous
    • Nomenclature : NOD-PrkdcscidIl
    • Strain : Repository Live
    • KI/KO Gene : B2m
    • Synonyms : Ly-m11,beta2m,b
  • hC5AR1

    hC5AR1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-C5a
    • Strain : Repository Live
    • KI/KO Gene : C5AR1
    • Synonyms : C5aR; C5r1; C
  • hCCL5

    hCCL5

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-CCL
    • Strain : Sperm cryoprese
    • KI/KO Gene : Ccl5
    • Synonyms : SISd; Scya5; RA
  • hCCL4

    hCCL4

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ccl
    • Strain : Embryo cryopres
    • KI/KO Gene : Ccl4
    • Synonyms : Act-2; Mip1b; S
  • hCB1

    hCB1

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Cnr
    • Strain : Repository Live
    • KI/KO Gene : Cnr1
    • Synonyms : CB1; CB-R; CB1R
  • hC5AR1/C5AR2

    hC5AR1/C5AR2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-C5a
    • Strain : Sperm cryoprese
    • KI/KO Gene : C5AR1
    • Synonyms : C5aR; C5r1; C
  • hIL21R

    hIL21R

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Repository Live
    • KI/KO Gene : IL21R
    • Synonyms : NILR
  • hIL21

    hIL21

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Repository Live
    • KI/KO Gene : IL21
    • Synonyms : IL-21
  • hIL2RA/hIL2RG

    hIL2RA/hIL2RG

    • Description : hIL2RG(NM-HU-20
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Embryo cryopres
    • KI/KO Gene : IL2RA
    • Synonyms : CD25; Il2r; I
  • hIL23A

    hIL23A

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Repository Live
    • KI/KO Gene : Il23a
    • Synonyms : p19 IL-23
  • hIL21R/hIL2RG

    hIL21R/hIL2RG

    • Description : hIL21R(NM-HU-21
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Embryo cryopres
    • KI/KO Gene : IL21R
    • Synonyms : NILR
  • hIL31

    hIL31

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il3
    • Strain : Repository Live
    • KI/KO Gene : Il31
    • Synonyms : 1700013B14Rik
  • hIL3/hCSF2/hCSF1

    hIL3/hCSF2/hCSF1

    • Description : hIL3(NM-HU-1900
    • Nomenclature : C57BL/6Smoc-Il3
    • Strain : Embryo cryopres
    • KI/KO Gene : CSF1
    • Synonyms : colony-stimulat
  • hIL3

    hIL3

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il3
    • Strain : Embryo cryopres
    • KI/KO Gene : IL3
    • Synonyms : BPA; PSF; HCG
  • hIL5-Tg(NMG,2)

    hIL5-Tg(NMG,2)

    • Description : These transgeni
    • Nomenclature : NOD-PrkdcscidIl
    • Strain : Sperm cryoprese
    • KI/KO Gene : Gt(ROSA)26Sor
    • Synonyms : R26,ROSA26,AV25
  • hIL4RA

    hIL4RA

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il4
    • Strain : Embryo cryopres
    • KI/KO Gene : Il4ra
    • Synonyms : Il4r, CD124
  • hIL4/hIL4R(BALB/c)

    hIL4/hIL4R(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Il
    • Strain : Repository Live
    • KI/KO Gene : IL4
    • Synonyms : Il-4; BSF-1