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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hIL6/hIL6R(M-NSG)

    hIL6/hIL6R(M-NSG)

    • Description : Model Descripti
    • Nomenclature : M-NSG-Il6tm(hIL
    • Strain : Repository Live
  • hKLRG1

    hKLRG1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Kl
    • Strain : Repository Live
    • KI/KO Gene : Klrg1
    • Synonyms : MAFA, 2F1-Ag, M
  • hLRRC15

    hLRRC15

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lr
    • Strain : Developing
    • KI/KO Gene : Lrrc15
    • Synonyms : LIB, 5430427N11
  • hMADCAM1

    hMADCAM1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Strain : Developing
    • KI/KO Gene : Madcam1
    • Synonyms : AV211525, MAdCA
  • hMSTN

    hMSTN

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ms
    • Strain : Developing
    • KI/KO Gene : Mstn
    • Synonyms : Cmpt, Gdf8
  • hNCR3LG1-Tg

    hNCR3LG1-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Tgtn( hNCR3LG1)
  • hMUC1

    hMUC1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mu
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Muc1
  • Myh6-CreERT2(SD)

    Myh6-CreERT2(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Myh6em(CreER
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Myh6
  • Myh6-Cre(SD)

    Myh6-Cre(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Myh6em(Cre)1
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Myh6
  • Lyz2-Cre(SD)

    Lyz2-Cre(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Lyz2em2(Cre)
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Lyz2
  • Park7-KO(SD)

    Park7-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Park7em1Smoc
    • Exon : Exon 3-5
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • Nr1i2-KO(SD)

    Nr1i2-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Nr1i2em1Smoc
    • Exon : Exon 3-4
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • Pvalb-IRES-Cre(SD)

    Pvalb-IRES-Cre(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Pvalbem1(IRE
    • Exon : Exon 3-4
    • Strain : Developing
    • Target : Immune Checkpoi
  • Ptgs2-KO(SD)

    Ptgs2-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Ptgs2em1Smoc
    • Exon : Exon 2-5
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • Pde4b-KO(SD)

    Pde4b-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Pde4bem3Smoc
    • Exon : Exon 7
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • Slc22a8-KO(SD)

    Slc22a8-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Slc22a8em1Sm
    • Exon : Exon 3-5
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • Slc22a1-KO(SD)

    Slc22a1-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Slc22a1em1Sm
    • Exon : Exon 2-3
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • Rag2-KO(SD)

    Rag2-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Rag2em1Smoc
    • Exon : Exon 3
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • C3ar1-2A-CreERT2

    C3ar1-2A-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-C3
    • Exon : Exon 3
    • Strain : Developing
    • Target : Immune Checkpoi
  • Ccr2-2A-DreERT2

    Ccr2-2A-DreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cc
    • Exon : Exon 3
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • Calca-Cre

    Calca-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ca
    • Exon : Exon 3
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • Cd207-2A-CreERT2

    Cd207-2A-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon 3
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • Cdkn1a-2A-Cre

    Cdkn1a-2A-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon 3
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • Cdh5-rtTA

    Cdh5-rtTA

    • Description : Model Descripti
    • Nomenclature : B6;129-Cdh5tm3(
    • Exon : Exon 3
    • Strain : Developing
    • Target : Immune Checkpoi
  • Cdh5-IRES-Mer-Cre-Me

    Cdh5-IRES-Mer-Cre-Me

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon 3
    • Strain : Developing
    • Target : Immune Checkpoi