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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • H2/H2-D1-KO(NMG)

    H2/H2-D1-KO(NMG)

    • Description : Exon 1-6 of H2;
    • Nomenclature : NOD-PrkdcscidIl
    • Strain : Developing
    • KI/KO Gene : H2-D1
    • Synonyms : H-2D, H2-D, H2-
  • Fcgr2b-Fcgr3-Fcgr4-KO/hCTLA-4

    • Description : The Fcgr2b-Fcgr
    • Nomenclature : C57BL/6Smoc-Fcg
    • Strain : Sperm cryoprese
    • KI/KO Gene : Fcgr2b
    • Synonyms : AI528646; CD32
  • hENTPD1(3)

    hENTPD1(3)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-En
    • Strain : Embryo cryopres
    • KI/KO Gene : Entpd1
    • Synonyms : Cd39, AA408691,
  • hENG

    hENG

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-En
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Eng
  • hEDNRA

    hEDNRA

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ed
    • Strain : Repository Live
    • Target : Tumor Targets
    • KI/KO Gene : Ednra
  • hF10

    hF10

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-F1
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : F10
  • hFCER1A

    hFCER1A

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fc
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Fcer1a
  • hGABPB1L

    hGABPB1L

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Gabpb1
  • hFGFR1

    hFGFR1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fg
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Fgfr1
  • hCD200R1

    hCD200R1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Cd200r1
  • hCD36(2)

    hCD36(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Cd36
  • hCD4(2)

    hCD4(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Cd4
  • hCD40/hCD40LG(BALB/c)

    hCD40/hCD40LG(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : CD40
  • hCD7(2)

    hCD7(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Cd7
  • hCD7

    hCD7

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Repository Live
    • Target : Tumor Targets
    • KI/KO Gene : Cd7
  • hCD47/hSIRPA(2)/hCD38(2)

    hCD47/hSIRPA(2)/hCD38(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Si
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : SIRPA
  • hCEBPA

    hCEBPA

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ce
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Cebpa
  • hCEACAM6-Tg

    hCEACAM6-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Tgtn(hCEACAM6)1
  • hADORA2A(BALB/c)

    hADORA2A(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Ad
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Adora2a
  • hADAM17

    hADAM17

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ad
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Adam17
  • hAPOB(1)

    hAPOB(1)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Strain : Developing
    • Target : Other Targets
    • KI/KO Gene : Apob
  • hAPOE3

    hAPOE3

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : Apoe
  • hCALCA

    hCALCA

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ca
    • Strain : Developing
    • Target : Metabolic Targe
    • KI/KO Gene : Calca
  • hIFNG

    hIFNG

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-If
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : Ifng
  • hIL2RA/hTNFRSF1B

    hIL2RA/hTNFRSF1B

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Strain : Developing
    • Target : Metabolic Targe
    • KI/KO Gene : TNFRSF1B