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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • Ghr-KO(2)

    Ghr-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gh
    • Exon : Exon 1-7.
    • Application : Peptide Ligand
    • Disease : Laron syndrome
  • Gck-Flox

    Gck-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gc
    • Exon : Exon s
    • Application : Peptide Ligand
    • Disease : Familial Hyperi
  • Gcdh-KO

    Gcdh-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gc
    • Exon : Exon 3-7
    • Application : Glutaric Acidem
    • Disease : Glutaric Acidem
  • Gbe1-KO

    Gbe1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gb
    • Exon : Exon 2
    • Application : Glutaric Acidem
    • Disease : Glycogen Storag
  • Gba-Flox

    Gba-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gb
    • Exon : Exon 8-11
    • Application : Gaucher Disease
    • Disease : Gaucher's Disea
  • Hnf4a-Flox

    Hnf4a-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Hn
    • Exon : Exon 2.
    • Application : Transcriptional
    • Disease : Fanconi Syndrom
  • Hif1a-Flox

    Hif1a-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Hi
    • Exon : Exon 2
    • Application : Hypoxia-Inducib
    • Disease : Von Hippel-Lind
  • Ikzf3-KO

    Ikzf3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ik
    • Exon : Exon 8
    • Application : Hypoxia-Inducib
    • Disease : Systemic Lupus
  • Krt14-R131C

    Krt14-R131C

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Kr
    • Exon : Exon 8
    • Application : Skin Diseases R
    • Disease : epidermolysis b
  • KPC

    KPC

    KPC

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Exon : Exon 8
    • Application : Spontaneous Pan
    • Disease : Pancreatic Carc
  • Lmx1a-Flox

    Lmx1a-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lm
    • Exon : Exon s
    • Application : Spontaneous Pan
    • Disease : Parkinson's Dis
  • Lmna-c.C1827T

    Lmna-c.C1827T

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lm
    • Exon : Exon s
    • Application : Spontaneous Pan
    • Disease : Progeria
  • Lepr-KO

    Lepr-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Le
    • Exon : Exon 5
    • Application : Obesity
    • Disease : Type 2 Diabetes
  • Mc4r-KO

    Mc4r-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mc
    • Exon : Exon 1
    • Application : Therapeutic Ant
    • Disease : obesity
  • Map6-KO

    Map6-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Exon : Exon 2
    • Application : Therapeutic Ant
    • Disease : Schizophrenia
  • Mafa-KO

    Mafa-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Exon : Exon 1
    • Application : Therapeutic Ant
    • Disease : type 2 diabetes
  • Madd-Flox

    Madd-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Exon : Exon s
    • Application : Therapeutic Ant
    • Disease : Type 2 Diabetes
  • Lrrtm1-KO

    Lrrtm1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Exon : Exon 2
    • Application : Therapeutic Ant
    • Disease : Schizophrenia
  • Ncstn-Flox

    Ncstn-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nc
    • Exon : Exon s
    • Application : Therapeutic Ant
    • Disease : Chronic Myeloid
  • Nrg3-KO

    Nrg3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Schizophrenia
  • Nphs2-A286V

    Nphs2-A286V

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Np
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Hereditary Glom
  • Pd-1-KO

    Pd-1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pd
    • Exon : Exon 2-4
    • Application : Immune-Related
    • Disease : Cystitis
  • Nrxn2-KO

    Nrxn2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 4-6
    • Application : Immune-Related
    • Disease : Autism Spectrum
  • Phox2a-KO

    Phox2a-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ph
    • Exon : Exon 2
    • Application : Immune-Related
    • Disease : Type 2 Diabetes
  • Ppp1r13l-KO

    Ppp1r13l-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pp
    • Exon : Exon 4-7
    • Application : Immune-Related
    • Disease : Arrhythmogenic