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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hTP53

    hTP53

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Strain : Developing
    • KI/KO Gene : Trp53
    • Synonyms : bbl, bfy, bhy,
  • hVEGFA

    hVEGFA

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ve
    • Strain : Repository Live
    • Target : Other Targets
    • KI/KO Gene : Vegfa
  • hTSLP

    hTSLP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ts
    • Strain : Embryo cryopres
    • Target : Cytokines
    • KI/KO Gene : Tslp
  • pCdh16-hENPP3-Tg

    pCdh16-hENPP3-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Tslp
  • pAlb-hAPOB-Tg

    pAlb-hAPOB-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Repository Live
    • Target : Metabolic Targe
    • KI/KO Gene : APOB
  • Ighm/Ighd-KO/hSIRPA/hCD47

    Ighm/Ighd-KO/hSIRPA/hCD47

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ig
    • Strain : Developing
    • Target : Metabolic Targe
    • KI/KO Gene : SIRPA
  • Rag2/IL2rg-KO/hCD40

    Rag2/IL2rg-KO/hCD40

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : CD40
  • Rorc-2A-tdTomato-2A-DTR

    Rorc-2A-tdTomato-2A-DTR

    • Description : T2A-tdTomato-P2
    • Nomenclature : C57BL/6Smoc-Ror
    • Strain : Sperm cryoprese
    • Target : Immune Checkpoi
    • KI/KO Gene : Rorc
  • Tmem119-2A-tdTomato

    Tmem119-2A-tdTomato

    • Description : A P2A-tdTomato
    • Nomenclature : C57BL/6Smoc-Tme
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Tmem119
  • hCLDN18.2-Tg

    hCLDN18.2-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Tmem119
  • hCXCR5

    hCXCR5

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cx
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Cxcr5
  • hENTPD1(2)

    hENTPD1(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-En
    • Strain : Embryo cryopres
    • Target : Cytokine Recept
    • KI/KO Gene : Entpd1
  • hF9

    hF9

    hF9

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-F9
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : F9
  • hFCGR3A

    hFCGR3A

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fc
    • Strain : Repository Live
    • Target : Cytokine Recept
    • KI/KO Gene : Fcgr4
  • hFCGR1B

    hFCGR1B

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fc
    • Strain : Embryo cryopres
    • Target : Cytokine Recept
    • KI/KO Gene : Fcgr1
  • hFOLR1

    hFOLR1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fo
    • Strain : Repository Live
    • Target : Cytokine Recept
    • KI/KO Gene : Folr1
  • hALDH2

    hALDH2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Aldh2
  • hANGPTL3(5)

    hANGPTL3(5)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-An
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Angptl3
  • hC1QA(2)

    hC1QA(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-C1
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : C1qa
  • hCCL2

    hCCL2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cc
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Ccl2
  • hCCN4

    hCCN4

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cc
    • Strain : Repository Live
    • Target : Cytokine Recept
    • KI/KO Gene : Ccn4
  • hCD123

    hCD123

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Il3ra
  • hCCR8(BALB/c)(2)

    hCCR8(BALB/c)(2)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Cc
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Ccr8
  • hCD19-Tg

    hCD19-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • Target : Tumor Targets
    • KI/KO Gene : Ccr8
  • hCD19

    hCD19

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Embryo cryopres
    • Target : Tumor Targets
    • KI/KO Gene : Cd19