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Animal Model
Shanghai Model Organisms Center, Inc.
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Animal Model
Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.
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Ly6g-2A-DTRGFP(BALB/c)
- Description : 2A-DTRGFP expre
- Nomenclature : BALB/cAnSmoc-Ly
- Strain : Repository Live
- KI/KO Gene : Ly6g
- Synonyms : Gr1; Gr-1; Ly-6
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Pdcd1-DTR-2A-tdTomato
- Description : A DTR-2A-tdToma
- Nomenclature : C57BL/6Smoc-Pdc
- Strain : Embryo cryopres
- KI/KO Gene : Pdcd1
- Synonyms : PD-1, Pdc1, Ly1
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Ncr1-IRES-mtagBFP2-Luc
- Description : A IRES-mtagBFP
- Nomenclature : C57BL/6Smoc-Ncr
- Strain : Embryo cryopres
- KI/KO Gene : Ncr1
- Synonyms : Ly94; NKp46
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R26-SA-LSL-DTR-IRES-tdTomato
- Description : A SA-LSL-DTR-IR
- Nomenclature : C57BL/6Smoc-Gt(
- Strain : Sperm cryoprese
- KI/KO Gene : Gt(ROSA)26Sor
- Synonyms : R26,ROSA26,AV25
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hSIGLEC15(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Siglec15
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hSIRPA(2)/hCD47/hPD-1
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Pdcd1
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hSIRPA(2)/hCD47/hCTLA-4
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Si
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : CTLA4
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hSTING(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-tm
- Strain : Repository Live
- Target : Immune Checkpoi
- KI/KO Gene : Tmem173
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hTIM3(BALB/c)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Ha
- Strain : Embryo cryopres
- Target : Immune Checkpoi
- KI/KO Gene : Havcr2
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hTIGIT(BALB/c,2)
- Description : Model Descripti
- Nomenclature : BALB/cAnSmoc-Ti
- Strain : Developing
- Target : Immune Checkpoi
- KI/KO Gene : Tigit
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hTNFSF11/hSIGLEC15
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Developing
- Target : Cytokines
- KI/KO Gene : TNFSF11
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hTNFRSF1B/hIL2RA
- Description : Model Descripti
- Nomenclature : C57BL/6JSmoc-Tn
- Strain : Embryo cryopres
- Target : Cytokines
- KI/KO Gene : TNFRSF1B
