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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hMASP1

    hMASP1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ma
    • Strain : Developing
    • KI/KO Gene : Masp1
    • Synonyms : CCPII,Crarf,Mas
  • hLRRC32

    hLRRC32

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lr
    • Strain : Developing
    • KI/KO Gene : Lrrc32
    • Synonyms : Garp, AI426318,
  • hMUC16

    hMUC16

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mu
    • Strain : Developing
    • KI/KO Gene : Muc16
    • Synonyms : Ca125, Gm1480,
  • hMUC1-c.462insC

    hMUC1-c.462insC

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mu
    • Strain : Repository Live
    • KI/KO Gene : Muc1
    • Synonyms : EMA, CD227, Muc
  • hNTRK2

    hNTRK2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nt
    • Strain : Developing
    • KI/KO Gene : Ntrk2
    • Synonyms : Tkrb, trkB, trk
  • hNTRK1

    hNTRK1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nt
    • Strain : Developing
    • KI/KO Gene : Ntrk1
    • Synonyms : Tkr, trk, TrkA,
  • hNOTCH3

    hNOTCH3

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-No
    • Strain : Developing
    • KI/KO Gene : Notch3
    • Synonyms : N3, hpbk, AW229
  • hPDGFB

    hPDGFB

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pd
    • Strain : Developing
    • KI/KO Gene : Pdgfb
    • Synonyms : Sis, c-sis, PDG
  • hREN(2)

    hREN(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Re
    • Strain : Repository Live
    • KI/KO Gene : Ren1
    • Synonyms : Ren, Rnr, Rn-1,
  • hIL2-Tg(NMG)

    hIL2-Tg(NMG)

    • Description : These transgeni
    • Nomenclature : NOD-PrkdcscidIl
    • Strain : Embryo cryopres
    • KI/KO Gene : IL2
    • Synonyms : Il-2
  • Foxp3-V5-AviTag-IRES-Luc-2A-tdTomato

    • Description : A V5-AviTag-IRE
    • Nomenclature : C57BL/6Smoc-Fox
    • Strain : Embryo cryopres
    • KI/KO Gene : Foxp3
    • Synonyms : sf; JM2; scurfi
  • hCD4(BALB/c)

    hCD4(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Cd
    • Strain : Embryo cryopres
    • KI/KO Gene : Cd4
    • Synonyms : L3T4; Ly-4
  • hFAP

    hFAP

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Fap
    • Strain : Developing
    • KI/KO Gene : Fap
    • Synonyms : SIMP
  • Il12b-Luc-2A-EGFP

    Il12b-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Embryo cryopres
    • KI/KO Gene : Il12b
    • Synonyms : CLMF CLMF2 IL-1
  • Ifng-Venus-Luc

    Ifng-Venus-Luc

    • Description : An IRES-Venus-L
    • Nomenclature : C57BL/6Smoc-Ifn
    • Strain : Embryo cryopres
    • KI/KO Gene : Ifng
    • Synonyms : Ifg IFN-gamma
  • Il1b-Luc-Tg

    Il1b-Luc-Tg

    • Description : The transgenic
    • Nomenclature : B6.Cg-Tg(IL1B-l
    • Strain : Repository Live
    • KI/KO Gene : IL1B
    • Synonyms : Il-1b; IL-1bet
  • Il1b-Luc-2A-EGFP

    Il1b-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Embryo cryopres
    • KI/KO Gene : IL1B
    • Synonyms : Il-1b; IL-1bet
  • Il1a-Luc-2A-EGFP

    Il1a-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Embryo cryopres
    • KI/KO Gene : Il1a
    • Synonyms : Il-1a
  • Il5-Luc-2A-EGFP

    Il5-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il5
    • Strain : Embryo cryopres
    • KI/KO Gene : Il5
    • Synonyms : Il-5
  • Il23a-Luc-2A-EGFP

    Il23a-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Embryo cryopres
    • KI/KO Gene : Il23a
    • Synonyms : p19 IL-23
  • Il1f6-Luc-2A-EGFP

    Il1f6-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Embryo cryopres
    • KI/KO Gene : Il1f6
    • Synonyms : Fil1 IL-1H1 IL1
  • Itgax-tdTomato-Luc

    Itgax-tdTomato-Luc

    • Description : A IRES-tdTomat
    • Nomenclature : C57BL/6Smoc-Itg
    • Strain : Embryo cryopres
    • KI/KO Gene : Itgax
    • Synonyms : Cr4; N418; Cd11
  • Itgax-IRES-DTRGFP

    Itgax-IRES-DTRGFP

    • Description : A IRES-DTREGFP
    • Nomenclature : C57BL/6Smoc-Itg
    • Strain : Embryo cryopres
    • KI/KO Gene : Itgax
    • Synonyms : Cr4; N418; Cd11
  • MHC Class II(I-A/I-E)-KO(Nod-Scid)

    • Description : All sequences f
    • Nomenclature : NOD-PrkdcscidH2
    • Strain : Developing
    • KI/KO Gene : H2-Ab1
    • Synonyms : IAb; Ia2; Ia-2;
  • MHC Class II (I-A/I-E) -KO

    • Description : All sequences f
    • Nomenclature : C57BL/6Smoc-H2-
    • Strain : Repository Live
    • KI/KO Gene : H2-Ab1
    • Synonyms : IAb; Ia2; Ia-2;