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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • R26-CAG-LSL-hNFE2L2*G81S-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Application : Cancer Research
    • KI/KO Gene : Gt(ROSA)26Sor
    • Synonyms : R26,ROSA26,AV25
  • Shank3-KO

    Shank3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sh
    • Exon : Exon 4-9
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • Scarb2-KO

    Scarb2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sc
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Progressive Myo
  • R26-LSL-Notch1C-IRES-nEGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 2
    • Application : Spontaneous Tum
    • Disease : Progressive Myo
  • Slc6a1-KO

    Slc6a1-KO

    • Description : Model Descripti
    • Nomenclature : B6;129S-Slc6a1t
    • Exon : Exon 2-3.
    • Application : Nervous System,
    • Disease : Schizophrenia
  • Slc37a4-KO

    Slc37a4-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 3
    • Application : Nervous System,
    • Disease : Glycogen Storag
  • Smad4-Flox

    Smad4-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sm
    • Exon : Exon 3-4
    • Application : Nervous System,
    • Disease : Osteogenesis Im
  • Slc9a9-KO

    Slc9a9-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Exon : Exon 2
    • Application : Nervous System,
    • Disease : autism spectrum
  • Syn1-KO

    Syn1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sy
    • Exon : Exon 4
    • Application : Nervous System,
    • Disease : Epilepsy
  • Stat1-KO

    Stat1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-St
    • Exon : Exon 4-5
    • Application : Cancer Research
    • Disease : Severe Acute Re
  • Tgm2-KO

    Tgm2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Exon : Exon 3-4
    • Application : Apoptosis, Gluc
    • Disease : Maturity-Onset
  • Tfam-Flox

    Tfam-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tf
    • Exon : Exon 10-13
    • Application : Activated Pkn1
    • Disease : Parkinson's Dis
  • Yme1l1-Flox

    Yme1l1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ym
    • Exon : Exon s
    • Application : Activated Pkn1
    • Disease : Dilated Cardiom
  • Usp1-Flox

    Usp1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Us
    • Exon : Exon 3
    • Application : Diseases Associ
    • Disease : Fanconi Anemia
  • Tyk2-KO

    Tyk2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ty
    • Exon : Exon 4
    • Application : Diseases Associ
    • Disease : Obesity
  • Tsc2-Flox

    Tsc2-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ts
    • Exon : Exon 3-5
    • Application : Diseases Associ
    • Disease : Uterine Fibroid
  • Zfp36-KO

    Zfp36-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Zf
    • Exon : Exon 2
    • Application : Diseases Associ
    • Disease : Rheumatoid Arth
  • hCD81/hOCLN

    hCD81/hOCLN

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon 2
    • Application : Hcv Infection R
    • Disease : Rheumatoid Arth
  • hIL5/hIL5R

    hIL5/hIL5R

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Exon : Exon 2
    • Application : Hcv Infection R
    • Disease : Rheumatoid Arth
  • hITGA5

    hITGA5

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-It
    • Exon : Exon 2
    • Application : Hcv Infection R
    • Disease : Rheumatoid Arth
  • hITGA4

    hITGA4

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-It
    • Exon : Exon 2
    • Application : Hcv Infection R
    • Disease : Rheumatoid Arth
  • hINSR

    hINSR

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-In
    • Exon : Exon 2
    • Application : Hcv Infection R
    • Disease : Rheumatoid Arth
  • hIL7(M-NSG)

    hIL7(M-NSG)

    • Description : Model Descripti
    • Nomenclature : M-NSG-Il7tm(hIL
    • Exon : Exon 2
    • Application : Hcv Infection R
    • Disease : Rheumatoid Arth
  • hKDR(BALB/c)

    hKDR(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Kd
    • Exon : Exon 2
    • Application : Hcv Infection R
    • Disease : Rheumatoid Arth
  • hLEPR

    hLEPR

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Le
    • Exon : Exon 2
    • Application : Hcv Infection R
    • Disease : Rheumatoid Arth