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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • Ldlr-KO(2)

    Ldlr-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ld
    • Exon : Exon 4.
    • Disease : familial hyperc
    • KI/KO Gene : Ldlr
  • Mecp2-Flox

    Mecp2-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon 2-3.
    • Application : Rett Syndrome,
    • Disease : Rett Syndrome
  • Mdm4-Flox

    Mdm4-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Md
    • Exon : Exon s
    • Application : Rett Syndrome,
    • Disease : Dilated Cardiom
  • Myocd-Flox

    Myocd-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-My
    • Exon : Exon s
    • Application : Rett Syndrome,
    • Disease : Patent Ductus A
  • Mertk-KO

    Mertk-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon 2
    • Application : Therapeutic Ant
    • Disease : Autoimmune Dise
  • Nipbl-Flox

    Nipbl-Flox

    • Description : Model Descripti
    • Nomenclature : B6;129S-Nipbltm
    • Exon : Exon 5
    • Application : Cornelia De Lan
    • Disease : Autoimmune Dise
  • Nexn-KO

    Nexn-KO

    • Description : Model Descripti
    • Nomenclature : B6;129S-Nipbltm
    • Exon : Exon 5-13
    • Application : Cornelia De Lan
    • Disease : dilated cardiom
  • Nexmif-KO

    Nexmif-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ne
    • Exon : Exon 4
    • Application : Cornelia De Lan
    • Disease : Autism Spectrum
  • Nrcam-KO

    Nrcam-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 5
    • Application : Cornelia De Lan
    • Disease : Autism Spectrum
  • Nphs2-R231Q

    Nphs2-R231Q

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Np
    • Exon : Exon 5
    • Application : Cornelia De Lan
    • Disease : Hereditary Glom
  • Pah-KO

    Pah-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pa
    • Exon : Exon 2-5
    • Application : Cornelia De Lan
    • Disease : Phenylketonuria
  • Opg-KO

    Opg-KO

    • Description : Model Descripti
    • Nomenclature : B6.129S-Tnfrsf1
    • Exon : Exon 2
    • Application : Osteoporosis
    • Disease : Phenylketonuria
  • Nrxn1-KO

    Nrxn1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 6
    • Application : Osteoporosis
    • Disease : Schizophrenia
  • Nrp2-KO

    Nrp2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 2
    • Application : Osteoporosis
    • Disease : Autism Spectrum
  • Pink1-KO

    Pink1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pi
    • Exon : Exon 2-4
    • Application : Mitochondrial H
    • Disease : Parkinson's Dis
  • Pdlim5-Flox

    Pdlim5-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pd
    • Exon : Exon s
    • Application : Mitochondrial H
    • Disease : Dilated Cardiom
  • Pnliprp1-KO

    Pnliprp1-KO

    • Description : Model Descripti
    • Nomenclature : B6;129S-Pnliprp
    • Exon : Exon 1
    • Application : Diabetes And Ob
    • Disease : Dilated Cardiom
  • Psen1-KO

    Psen1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ps
    • Exon : Exon 4
    • Application : Diabetes And Ob
    • Disease : Systemic Lupus
  • Psen1-Flox

    Psen1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ps
    • Exon : Exon s
    • Application : Diabetes And Ob
    • Disease : Alzheimer's Dis
  • Prlh-KO

    Prlh-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pr
    • Exon : Exon 2
    • Application : Diabetes And Ob
    • Disease : Obesity
  • Prex1-KO

    Prex1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pr
    • Exon : Exon 6-7
    • Application : Diabetes And Ob
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hEGFR*L858R/T790M/C797S-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 6-7
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hEGFR*L858R/T790M-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 6-7
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hBCR/ABL

    R26-CAG-LSL-hBCR/ABL

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 6-7
    • Application : Chronic Myelocy
    • Disease : Autism Spectrum
  • R26-CAG-LSL-hEML4/ALK*F1174L-Luc-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 6-7
    • Application : Cancer
    • Disease : Autism Spectrum