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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • Cox10-Flox

    Cox10-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Co
    • Exon : Exon s
    • Disease : Parkinson's Dis
    • KI/KO Gene : Cox10
  • Cntnap2-KO

    Cntnap2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cn
    • Exon : Exon 4
    • Disease : Cortical Dyspla
    • KI/KO Gene : Cntnap2
  • Chst3-KO

    Chst3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ch
    • Exon : Exon 4
    • Disease : Schizophrenia
    • KI/KO Gene : Chst3
  • Cenpf-Flox

    Cenpf-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ce
    • Exon : Exon 3
    • Disease : Dilated Cardiom
    • KI/KO Gene : Cenpf
  • Cyp4v3-KO

    Cyp4v3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cy
    • Exon : Exon 2-6
    • Disease : Bietti Crystall
    • KI/KO Gene : Cyp4v3
  • Dicer1-Flox

    Dicer1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Di
    • Exon : Exon 23
    • Application : Hypoxia-Mediate
    • Disease : Ovarian Cancer
  • F8-KO

    F8-KO

    • Description : Model Descripti
    • Nomenclature : B6.129S-F8tm1Sm
    • Exon : Exon 16-19.
    • Application : Hemophilia A;He
    • Disease : Factor Viii Def
  • Eif4ebp2-KO

    Eif4ebp2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ei
    • Exon : Exon 3-4
    • Application : Cell Proliferat
    • Disease : Autism Spectrum
  • Efhc1-KO

    Efhc1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ei
    • Exon : Exon 3-5
    • Application : Cell Proliferat
    • Disease : Juvenile Myoclo
  • Drd2-KO

    Drd2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Dr
    • Exon : Exon 3
    • Application : Immune-Related
    • Disease : Juvenile Myoclo
  • F9-KO

    F9-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-F9
    • Exon : Exon 8
    • Application : Factor Ix (F9)
    • Disease : Hemophilia B
  • Gata5-KO

    Gata5-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Exon : Exon 2
    • Application : Factor Ix (F9)
    • Disease : Essential Hyper
  • Gabrb3-KO

    Gabrb3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Exon : Exon 2-3
    • Application : Factor Ix (F9)
    • Disease : Autism Spectrum
  • Ghr-KO

    Ghr-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gh
    • Exon : Exon 4.
    • Application : Cardiovascular
    • Disease : Laron Syndrome
  • Gstm1-KO

    Gstm1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gs
    • Exon : Exon 2
    • Application : Cardiovascular
    • Disease : Autism Spectrum
  • Grm5-KO

    Grm5-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gr
    • Exon : Exon 4
    • Application : Endocrine, Cort
    • Disease : Schizophrenia
  • Gpr143-KO

    Gpr143-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gp
    • Exon : Exon 2
    • Application : Endocrine, Cort
    • Disease : Ocular Albinism
  • hTNFa-Tg(DBA)

    hTNFa-Tg(DBA)

    • Description : Model Descripti
    • Nomenclature : DBA-Tg(hTNFa)1S
    • Exon : Exon 2
    • Application : Arthritis Mouse
    • Disease : Ocular Albinism
  • Hmga1-KO

    Hmga1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Hm
    • Exon : Exon 3-5
    • Application : Arthritis Mouse
    • Disease : Type 2 Diabetes
  • Hivep2-KO

    Hivep2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Hm
    • Exon : Exon 5
    • Application : Arthritis Mouse
    • Disease : Schizophrenia
  • Lat-Y136F

    Lat-Y136F

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-La
    • Exon : Exon 5
    • Application : Igg4-Related Di
    • Disease : Igg4-Related Di
  • Kras-LSL-G12D

    Kras-LSL-G12D

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Kr
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Squamous Cell C
  • KPC(2)

    KPC(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Exon : Exon 2
    • Application : Spontaneous Pan
    • Disease : pancreatic carc
  • Lmx1b-Flox

    Lmx1b-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lm
    • Exon : Exon 4-6
    • Application : Research On Dop
    • Disease : Nail-Patella Sy
  • Lep-KO

    Lep-KO

    • Description : Model Descripti
    • Nomenclature : B6;129S-Leptm1S
    • Exon : Exon 2
    • Application : Insulin Resista
    • Disease : Abdominal Obesi