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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • R26-CAG-LSL-Kdm7a-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Strain : Embryo cryopres
    • KI/KO Gene : Gt(ROSA)26Sor
    • Synonyms : R26, ROSA26, AV
  • R26-CAG-LSL-zsGreen

    R26-CAG-LSL-zsGreen

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Strain : Repository Live
    • KI/KO Gene : Gt(ROSA)26Sor
    • Synonyms : R26, ROSA26, AV
  • R26-CAG-LSL-RSR-tdTomato-2A-DTR

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Strain : Repository Live
    • KI/KO Gene : Gt(ROSA)26Sor
    • Synonyms : R26, ROSA26, AV
  • R26-LNL-PB

    R26-LNL-PB

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Strain : Embryo cryopres
    • KI/KO Gene : Gt(ROSA)26Sor
    • Synonyms : R26, ROSA26, AV
  • R26-CreERT2(2)

    R26-CreERT2(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Strain : Repository Live
    • KI/KO Gene : Gt(ROSA)26Sor
    • Synonyms : R26, ROSA26, AV
  • Ren1-2A-CreERT2

    Ren1-2A-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Re
    • Strain : Embryo cryopres
    • KI/KO Gene : Ren1
    • Synonyms : Ren, Rnr, Rn-1,
  • R26-ZsGreen-L-Stop-tdTomato-2A-tdTomato-Polyloxexpress

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Strain : Developing
    • KI/KO Gene : Gt(ROSA)26Sor
    • Synonyms : R26, ROSA26, AV
  • Scaf1-Loxp-LacZ-Loxp

    Scaf1-Loxp-LacZ-Loxp

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sc
    • Strain : Sperm cryoprese
    • KI/KO Gene : Scaf1
    • Synonyms : SR-A1, AI480556
  • Satb2-IRES-CreERT2

    Satb2-IRES-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sa
    • Strain : Developing
    • KI/KO Gene : Satb2
    • Synonyms : BAP002;mKIAA103
  • Sftpc-IRES-Cre

    Sftpc-IRES-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sf
    • Strain : Developing
    • KI/KO Gene : Sftpc
    • Synonyms : SP5, SPC, SP-C,
  • Sox10-2A-Cre

    Sox10-2A-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-So
    • Strain : Repository Live
    • KI/KO Gene : Sox10
    • Synonyms : gt , Dom, Sox21
  • Slc7a14-2A-Dre

    Slc7a14-2A-Dre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Sl
    • Strain : Developing
    • KI/KO Gene : Slc7a14
    • Synonyms : BC061928, A9300
  • Sst-IRES-CreERT2

    Sst-IRES-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ss
    • Strain : Repository Live
    • KI/KO Gene : Sst
    • Synonyms : SS, SOM, SRIF,
  • Tcf7-2A-EGFP-2A-CreERT

    Tcf7-2A-EGFP-2A-CreERT

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tc
    • Strain : Developing
    • KI/KO Gene : Tcf7
    • Synonyms : TCF-1;Tcf1
  • Tbx21-T2A-Cre

    Tbx21-T2A-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tb
    • Strain : Developing
    • KI/KO Gene : Tbx21
    • Synonyms : TBT1, Tbet, Tbl
  • Aldh1L2-KO

    Aldh1L2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Exon : Exon 2
    • Disease : Non-Alcoholic F
    • Strain : Developing
  • Akt2-KO

    Akt2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ak
    • Exon : Exon 3-4
    • Application : Signal Transduc
    • Disease : Type 2 Diabetes
  • Agxt-KO

    Agxt-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ag
    • Exon : Exon 3-8
    • Application : Signal Transduc
    • Disease : Primary Hyperox
  • Adk-KO

    Adk-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ad
    • Exon : Exon 4
    • Application : Signal Transduc
    • Disease : Fatty Liver Dis
  • Alms1-del(c.3802-3812)

    Alms1-del(c.3802-3812)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Al
    • Exon : Exon 4
    • Application : Alström Syndrom
    • Disease : Fatty Liver Dis
  • Bckdk-KO

    Bckdk-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Bc
    • Exon : Exon 9-12
    • Application : Alström Syndrom
    • Disease : Autism Spectrum
  • Braf-Flox-V600E

    Braf-Flox-V600E

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Br
    • Exon : Exon 9-12
    • Application : Cancer Research
    • Disease : Autism Spectrum
  • Braf-Flox

    Braf-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Br
    • Exon : Exon 5
    • Application : Study On The Co
    • Disease : Melanoma
  • Cdyl-Flox

    Cdyl-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon s
    • Application : Study On The Co
    • Disease : Epilepsy
  • Cd200-KO

    Cd200-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Exon : Exon 2
    • Application : Immune-Related
    • Disease : Epilepsy