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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hAPOB(2)

    hAPOB(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ap
    • Strain : Developing
    • KI/KO Gene : Apob
    • Synonyms : Apo B-100,apob-
  • hANGPTL8

    hANGPTL8

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-An
    • Strain : Developing
    • KI/KO Gene : Angptl8
    • Synonyms : Rifl, Gm6484, E
  • hB4GALNT1

    hB4GALNT1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-B4
    • Strain : Developing
    • KI/KO Gene : B4galnt1
    • Synonyms : Ggm2, Ggm-2, Ga
  • hCCR7

    hCCR7

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cc
    • Strain : Developing
    • KI/KO Gene : Ccr7
    • Synonyms : EBI1, CCR-7, CD
  • hCD14

    hCD14

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • KI/KO Gene : Cd14
    • Synonyms : EBI1, CCR-7, CD
  • hCD22(BALB/c)

    hCD22(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Cd
    • Strain : Developing
    • KI/KO Gene : Cd22
    • Synonyms : Lyb8, Lyb-8, A5
  • hCD3EDG/hB7H3

    hCD3EDG/hB7H3

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : CD276
  • hCD70

    hCD70

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Cd70
  • hCD47(BALB/c)

    hCD47(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Cd
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Cd47
  • hCEACAM1(2)

    hCEACAM1(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ce
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Ceacam1
  • hCDH3

    hCDH3

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Cdh3
  • hCDH17

    hCDH17

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • Target : Immune Checkpoi
    • KI/KO Gene : Cdh17
  • Fah-KO(NMG)

    Fah-KO(NMG)

    • Description : Exon 3 of Fah g
    • Nomenclature : NOD-PrkdcscidIl
    • Strain : Sperm cryoprese
    • Target : Immune Checkpoi
    • KI/KO Gene : Fah
  • Foxp3-IRES-Luc-2A-tdTomato

    • Description : A IRES-luci-2A
    • Nomenclature : C57BL/6Smoc-Fox
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Foxp3
  • Il4-Luc-2A-EGFP

    Il4-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il4
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : IL4
  • Il4-IRES-tdTomato

    Il4-IRES-tdTomato

    • Description : A IRES-tdTomat
    • Nomenclature : C57BL/6Smoc-Il4
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Il4
  • Il3-Luc-2A-EGFP

    Il3-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il3
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Il3
  • Il20-IRES-Luc-2A-EGFP

    Il20-IRES-Luc-2A-EGFP

    • Description : A IRES-Lucifer
    • Nomenclature : C57BL/6Smoc-Il2
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Il20
  • Lyz2-IRES-mtagBFP2-Luc

    Lyz2-IRES-mtagBFP2-Luc

    • Description : A IRES-mtagBFP
    • Nomenclature : C57BL/6Smoc-Lyz
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Lyz2
  • pAlb-TK-IRES-luc-2A-EGFP-Tg(NMG)

    • Description : These transgeni
    • Nomenclature : NOD-PrkdcscidIl
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : TK1
  • NMG-Hc(NMG)

    NMG-Hc(NMG)

    • Description : These NMG mice
    • Nomenclature : NOD-PrkdcscidIl
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Hc
  • Tmem119-2A-DTRGFP

    Tmem119-2A-DTRGFP

    • Description : A P2A-DTRGFP ex
    • Nomenclature : C57BL/6Smoc-Tme
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • KI/KO Gene : Tmem119
  • Ndufs2-KO(SD)

    Ndufs2-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Ndufs2em1Smo
    • Exon : Exon 5-7
    • Strain : Developing
    • Target : Immune Checkpoi
  • Mecp2-Flox(SD)

    Mecp2-Flox(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Mecp2em1(flo
    • Exon : Exon 2-3
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • Lrrk1-KO(SD)

    Lrrk1-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Lrrk1em1Smoc
    • Exon : Exon 2
    • Strain : Repository Live
    • Target : Immune Checkpoi