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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • Itgax-tdTomato-Luc

    Itgax-tdTomato-Luc

    • Strain : Embryo cryopres
    • KI/KO Gene : Itgax
    • Research Application : Tool Mice
    • Nomenclature : C57BL/6Smoc-Itg
    • Description : A IRES-tdTomat
  • Itgax-IRES-DTRGFP

    Itgax-IRES-DTRGFP

    • Strain : Embryo cryopres
    • KI/KO Gene : Itgax
    • Research Application : Dtr Mouse
    • Nomenclature : C57BL/6Smoc-Itg
    • Description : A IRES-DTREGFP
  • MHC Class II(I-A/I-E)-KO(Nod-Scid)

    • Strain : Developing
    • KI/KO Gene : H2-Ab1
    • Research Application : Immune System
    • Nomenclature : NOD-PrkdcscidH2
    • Description : All sequences f
  • MHC Class II (I-A/I-E) -KO

    • Strain : Repository Live
    • KI/KO Gene : H2-Ab1
    • Research Application : Immune System
    • Nomenclature : C57BL/6Smoc-H2-
    • Description : All sequences f
  • Ly6g-2A-DTRGFP(BALB/c)

    Ly6g-2A-DTRGFP(BALB/c)

    • Strain : Repository Live
    • KI/KO Gene : Ly6g
    • Research Application : Inducible Cell
    • Nomenclature : BALB/cAnSmoc-Ly
    • Description : 2A-DTRGFP expre
  • Pdcd1-DTR-2A-tdTomato

    Pdcd1-DTR-2A-tdTomato

    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Research Application : Dtr Tool Mice
    • Nomenclature : C57BL/6Smoc-Pdc
    • Description : A DTR-2A-tdToma
  • NVG-hIL15

    NVG-hIL15

    • Strain : Embryo cryopres
    • KI/KO Gene : Il15
    • Research Application : Immunotherapy
    • Nomenclature : NOD.Cg-Prkdcsci
    • Description : The endogenous
  • NMG

    NMG

    NMG

    • Strain : Repository Live
    • KI/KO Gene : Il2rg
    • Nomenclature : NOD.Cg-Prkdcsci
    • Research Application : Immune And Hema
    • Description : Prkdc and Il2rg
  • Ncr1-IRES-mtagBFP2-Luc

    Ncr1-IRES-mtagBFP2-Luc

    • Strain : Embryo cryopres
    • KI/KO Gene : Ncr1
    • Research Application : Nk Cell Reporte
    • Nomenclature : C57BL/6Smoc-Ncr
    • Description : A IRES-mtagBFP
  • R26-SA-LSL-DTR-IRES-tdTomato

    • Strain : Sperm cryoprese
    • KI/KO Gene : Gt(ROSA)26Sor
    • Research Application : Dtr Tool Mice
    • Nomenclature : C57BL/6Smoc-Gt(
    • Description : A SA-LSL-DTR-IR
  • hSIGLEC15(BALB/c)

    hSIGLEC15(BALB/c)

    • Nomenclature : BALB/cAnSmoc-Si
    • KI/KO Gene : Siglec15
    • Research Application : Immunotherapy
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • hSERPINC1

    hSERPINC1

    • Nomenclature : C57BL/6JSmoc-Se
    • KI/KO Gene : Serpinc1
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti
  • hSIRPA(2)/hCD47/hPD-1

    hSIRPA(2)/hCD47/hPD-1

    • Nomenclature : C57BL/6JSmoc-Si
    • KI/KO Gene : Pdcd1
    • Research Application : Immune-related
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • hSIRPA(2)/hCD47/hCTLA-4

    hSIRPA(2)/hCD47/hCTLA-4

    • Nomenclature : C57BL/6JSmoc-Si
    • KI/KO Gene : CTLA4
    • Research Application : Immunotherapy
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • hSIRPA(2)

    hSIRPA(2)

    • Nomenclature : C57BL/6JSmoc-Si
    • KI/KO Gene : Sirpa
    • Research Application : Immunotherapy
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • hSOST

    hSOST

    • Nomenclature : C57BL/6JSmoc-So
    • KI/KO Gene : Sost
    • Strain : Repository Live
    • Target : Other Targets
    • Description : Model Descripti
  • hSNCA

    hSNCA

    • Nomenclature : C57BL/6JSmoc-Sn
    • KI/KO Gene : Snca
    • Strain : Developing
    • Target : Other Targets
    • Description : Model Descripti
  • hSLC7A5

    hSLC7A5

    • Nomenclature : C57BL/6JSmoc-Sl
    • KI/KO Gene : Slc7a5
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : TA1, LAT1, 4F2L
  • hSTING(BALB/c)

    hSTING(BALB/c)

    • Nomenclature : BALB/cAnSmoc-tm
    • KI/KO Gene : Tmem173
    • Research Application : Immunotherapy
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • hTIM3(BALB/c)

    hTIM3(BALB/c)

    • Nomenclature : BALB/cAnSmoc-Ha
    • KI/KO Gene : Havcr2
    • Research Application : Immunotherapy
    • Strain : Embryo cryopres
    • Description : Model Descripti
  • hTIGIT(BALB/c,2)

    hTIGIT(BALB/c,2)

    • Nomenclature : BALB/cAnSmoc-Ti
    • KI/KO Gene : Tigit
    • Strain : Developing
    • Target : Immune Checkpoi
    • Description : Model Descripti
  • hTIGIT(3)

    hTIGIT(3)

    • Nomenclature : C57BL/6JSmoc-Ti
    • KI/KO Gene : Tigit
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • Description : Model Descripti
  • hTIMD4

    hTIMD4

    • Nomenclature : C57BL/6JSmoc-Ti
    • KI/KO Gene : Timd4
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
    • Description : Model Descripti
  • hTNFRSF1B

    hTNFRSF1B

    • Nomenclature : C57BL/6JSmoc-Tn
    • KI/KO Gene : Tnfrsf1b
    • Research Application : Immune-related
    • Strain : Repository Live
    • Description : Model Descripti
  • hTNFa-Tg

    hTNFa-Tg

    • Nomenclature : C57BL/6JSmoc-Tg
    • KI/KO Gene : TNF
    • Strain : Sperm cryoprese
    • Target : Cytokines
    • Description : Model Descripti