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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • Eif2ak4-2A-Cre

    Eif2ak4-2A-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ei
    • Strain : Developing
    • KI/KO Gene : Eif2ak4
    • Synonyms : GCN2, MGCN2, 26
  • Dbx1-IRES-CreERT2

    Dbx1-IRES-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Db
    • Strain : Repository Live
    • KI/KO Gene : Dbx1
    • Synonyms : Dbx, AI426026
  • Eno2-2A-CreERT2

    Eno2-2A-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-En
    • Strain : Embryo cryopres
    • KI/KO Gene : Eno2
    • Synonyms : NSE, Eno-2, A
  • Flt3-2A-DreERT2

    Flt3-2A-DreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fl
    • Strain : Embryo cryopres
    • KI/KO Gene : Flt3
    • Synonyms : Flk2, Ly72, w
  • Flt3-2A-CreERT2

    Flt3-2A-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fl
    • Strain : Developing
    • KI/KO Gene : Flt3
    • Synonyms : B230315G04;CD13
  • Far2-IRES-Cre

    Far2-IRES-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fa
    • Strain : Developing
    • KI/KO Gene : Far2
    • Synonyms : A230046P18;Mlst
  • Foxp1-2A-Cre

    Foxp1-2A-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fo
    • Strain : Developing
    • KI/KO Gene : Foxp1
    • Synonyms : AI461938, AW494
  • Glp1r-IRES-Cre

    Glp1r-IRES-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gl
    • Strain : Embryo cryopres
    • KI/KO Gene : Glp1r
    • Synonyms : GLP-1R, GLP1Rc
  • Gad2-CreERT2

    Gad2-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Strain : Repository Live
    • KI/KO Gene : Gad2
    • Synonyms : GAD65, Gad-2, G
  • Foxp3-IRES-tdTomato-2A-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Fo
    • Strain : Repository Live
    • KI/KO Gene : Foxp3
    • Synonyms : sf, JM2, scur
  • Hopx-IRES-CreERT2

    Hopx-IRES-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ho
    • Strain : Embryo cryopres
    • KI/KO Gene : Hopx
    • Synonyms : Hod, Hop, Ob1
  • Hopx-2A-DreERT2

    Hopx-2A-DreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ho
    • Strain : Repository Live
    • KI/KO Gene : Hopx
    • Synonyms : 1110018K11Rik 1
  • Hlf-CreERT2

    Hlf-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Hl
    • Strain : Developing
    • KI/KO Gene : Hlf
    • Synonyms : E230015K02Rik
  • Il17a-Cre

    Il17a-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Strain : Embryo cryopres
    • KI/KO Gene : Il17a
    • Synonyms : Il17, Ctla8,
  • Isl1-Dre

    Isl1-Dre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Is
    • Strain : Repository Live
    • KI/KO Gene : Isl1
    • Synonyms : Il17, Ctla8,
  • Iqgap3-2A-CreERT2(2)

    Iqgap3-2A-CreERT2(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Iq
    • Strain : Developing
    • KI/KO Gene : Iqgap3
    • Synonyms : D030034H08
  • Krt17-2A-CreERT2

    Krt17-2A-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Kr
    • Strain : Developing
    • KI/KO Gene : Krt17
    • Synonyms : K17;Krt1-17
  • Kcng4-Cre

    Kcng4-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Kc
    • Strain : Embryo cryopres
    • KI/KO Gene : Kcng4
    • Synonyms : KV6.3, KV6.4,
  • Lgr5-EGFP-IRES-CreERT2

    Lgr5-EGFP-IRES-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lg
    • Strain : Repository Live
    • KI/KO Gene : Lgr5
    • Synonyms : FEX, Gpr49
  • Lgr5-2A-DreERT2

    Lgr5-2A-DreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lg
    • Strain : Sperm cryoprese
    • KI/KO Gene : Lgr5
    • Synonyms : FEX, Gpr49
  • Lepr-RSR-CreERT2

    Lepr-RSR-CreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Le
    • Strain : Embryo cryopres
    • KI/KO Gene : Lepr
    • Synonyms : db, Obr, obl, L
  • Ltf-Cre-IRES-tdTomato

    Ltf-Cre-IRES-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lt
    • Strain : Repository Live
    • KI/KO Gene : Ltf
    • Synonyms : Lf, Csp82, Ms
  • Mki67-RSR-2A-Cre

    Mki67-RSR-2A-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6-Mki67em
    • Strain : Repository Live
    • KI/KO Gene : Mki67
    • Synonyms : Ki67, Ki-67, D6
  • Meox1-Dre

    Meox1-Dre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Me
    • Strain : Developing
    • KI/KO Gene : Meox1
    • Synonyms : Mox1, Mox-1,
  • Lyz2-DreERT2

    Lyz2-DreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ly
    • Strain : Developing
    • KI/KO Gene : Lyz2
    • Synonyms : Lys, Lysm, Lyzf