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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hIL13

    hIL13

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Embryo cryopres
    • KI/KO Gene : IL13
    • Synonyms : IL-13; P600
  • hIL12RB2

    hIL12RB2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Repository Live
    • KI/KO Gene : Ccr4
    • Synonyms : LESTR; Sdf1r; C
  • hIL12A/hIL12B/hIL12RB1/hIL12RB2

    • Description : hIL12A(NM-HU-20
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Developing
    • KI/KO Gene : Il12b
    • Synonyms : p40, Il-12b, Il
  • hIL11

    hIL11

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Embryo cryopres
    • KI/KO Gene : Il11
    • Synonyms : IL-11
  • hIL18

    hIL18

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Sperm cryoprese
    • KI/KO Gene : Il18
    • Synonyms : Igif; Il-18
  • hIL17A

    hIL17A

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Embryo cryopres
    • KI/KO Gene : IL17A
    • Synonyms : Il17; Ctla8; IL
  • hIL1B(BALB/c)

    hIL1B(BALB/c)

    • Description : The endogenous
    • Nomenclature : BALB/cAnSmoc-Il
    • Strain : Repository Live
    • KI/KO Gene : IL1B
    • Synonyms : Il-1b; IL-1bet
  • hIL1B

    hIL1B

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Il1
    • Strain : Repository Live
    • KI/KO Gene : Il1b
    • Synonyms : Il-1b, IL-1beta
  • hTHPO

    hTHPO

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Thp
    • Strain : Embryo cryopres
    • KI/KO Gene : Thpo
    • Synonyms : Ml, Tpo, Mgdf,
  • hTLR9/hOX40

    hTLR9/hOX40

    • Description : This TLR9 and O
    • Nomenclature : C57BL/6Smoc-Tlr
    • Strain : Embryo cryopres
    • KI/KO Gene : Tnfrsf4
    • Synonyms : Ox40; ACT35;
  • hTLR9

    hTLR9

    • Description : This TLR9 human
    • Nomenclature : C57BL/6Smoc-Tlr
    • Strain : Embryo cryopres
    • KI/KO Gene : Tlr9
    • Synonyms : Ox40; ACT35;
  • hTLR8/Lyz2-DTREGFP

    hTLR8/Lyz2-DTREGFP

    • Description : NM-KI-190041 wa
    • Nomenclature : C57BL/6Smoc-Lyz
    • Strain : Embryo cryopres
    • KI/KO Gene : TLR8
    • Synonyms : Ox40; ACT35;
  • hTLR4

    hTLR4

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tlr
    • Strain : Embryo cryopres
    • KI/KO Gene : Tlr4
    • Synonyms : Lps; Ly87; Ran/
  • hTIGIT/hTNFR2

    hTIGIT/hTNFR2

    • Description : hTIGIT(3)(NM-HU
    • Nomenclature : C57BL/6Smoc-Tig
    • Strain : Repository Live
    • KI/KO Gene : CTLA4
    • Synonyms : Cd152; Ly-56;
  • hTNFR2/hPD-1

    hTNFR2/hPD-1

    • Description : hTNFRSF1B(NM-HU
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hTNFR2

    hTNFR2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Repository Live
    • KI/KO Gene : TNFRSF1B
    • Synonyms : p75; TNFBR; T
  • hTSLP/hIL17RA

    hTSLP/hIL17RA

    • Description : hTSLP(NM-HU-200
    • Nomenclature : C57BL/6Smoc-Tsl
    • Strain : Embryo cryopres
    • KI/KO Gene : TSLP
    • Synonyms : p75; TNFBR; T
  • hTSLP

    hTSLP

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tsl
    • Strain : Embryo cryopres
    • KI/KO Gene : TSLP
    • Synonyms : p75; TNFBR; T
  • hTROP2

    hTROP2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tac
    • Strain : Repository Live
    • KI/KO Gene : Tacstd2
    • Synonyms : Ly97; EGP-1; TR
  • hTNFSF13B

    hTNFSF13B

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Tnf
    • Strain : Developing
    • KI/KO Gene : Tnfsf13b
    • Synonyms : BAFF, BLyS, TAL
  • hVEGFR2

    hVEGFR2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Kdr
    • Strain : Embryo cryopres
    • KI/KO Gene : KDR
    • Synonyms : KDR
  • Itgam-IRES-hCD89/hIGHA1

    Itgam-IRES-hCD89/hIGHA1

    • Description : Itgam-IRES-hCD8
    • Nomenclature : C57BL/6Smoc-Itg
    • Strain : Repository Live
    • KI/KO Gene : Itgam
    • Synonyms : CR3; CR3A; MA
  • R26-LSL-hIL15-Flag-IRES-EGFP

    • Description : CAG-Loxp-Stop-L
    • Nomenclature : C57BL/6Smoc-Gt(
    • Strain : Sperm cryoprese
    • KI/KO Gene : Gt(ROSA)26Sor
    • Synonyms : R26,ROSA26,AV25
  • hPD-1/hSIRPA(2)

    hPD-1/hSIRPA(2)

    • Description : hPD-1(NM-HU-000
    • Nomenclature : C57BL/6Smoc-Pdc
    • Strain : Embryo cryopres
    • KI/KO Gene : Pdcd1
    • Synonyms : PD-1; Pdc1; Ly1
  • hPD-L1(2)

    hPD-L1(2)

    • Description : Extracellular d
    • Nomenclature : C57BL/6Smoc-Cd2
    • Strain : Embryo cryopres
    • KI/KO Gene : Cd274
    • Synonyms : B7h1; Pdl1; P