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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hTNFRSF1B/hFCGR2B

    hTNFRSF1B/hFCGR2B

    • Nomenclature : C57BL/6JSmoc-Tn
    • KI/KO Gene : Fcgr2b
    • Research Application : Immunotherapy
    • Strain : Developing
    • Description : Model Descripti
  • hTNFSF15(BALB/c)

    hTNFSF15(BALB/c)

    • Nomenclature : BALB/cAnSmoc-Tn
    • KI/KO Gene : Tnfsf15
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Tl1, Tl1a, Vegi
  • hVEGFC

    hVEGFC

    • Nomenclature : C57BL/6JSmoc-Ve
    • KI/KO Gene : Vegfc
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : VEGF-C, AW22885
  • R26-CAG-LSL-hPLA2R1-IRES-EGFP

    • Nomenclature : C57BL/6JSmoc-Gt
    • KI/KO Gene : Pla2r1
    • Strain : Developing
    • Target : Other Targets
    • Description : Model Descripti
  • Itgam-IRES-hCD89/hMASP2

    Itgam-IRES-hCD89/hMASP2

    • Nomenclature : C57BL/6JSmoc-It
    • KI/KO Gene : Itgam
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : CR3, CR3A, MA
  • hXDH

    hXDH

    • Nomenclature : C57BL/6JSmoc-Xd
    • KI/KO Gene : Xdh
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : XO,Xor,Xox-1,Xo
  • Rag2/IL2rg-KO/hSIRPA(2)/hCD47

    • Nomenclature : C57BL/6JSmoc-Si
    • KI/KO Gene : IL2RG
    • Research Application : Immunotherapy
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • Rag2-KO/hKDR

    Rag2-KO/hKDR

    • Nomenclature : C57BL/6JSmoc-Kd
    • KI/KO Gene : Rag2
    • Strain : Embryo cryopres
    • Description : Model Descripti
    • Synonyms : Rag-2
  • R26-LSL-hIL5(M-NSG)

    R26-LSL-hIL5(M-NSG)

    • Nomenclature : NOD-PrkdcscidIl
    • KI/KO Gene : Gt(ROSA)26Sor
    • Strain : Repository Live
    • Description : Model Descripti
    • Synonyms : R26, ROSA26, AV
  • Rag2-KO

    Rag2-KO

    • Strain : Repository Live
    • KI/KO Gene : Rag2
    • Research Application : Immunodeficienc
    • Nomenclature : C57BL/6Smoc-Rag
    • Description : Partial exon 3
  • Txlna-Luc-EGFP

    Txlna-Luc-EGFP

    • Strain : Embryo cryopres
    • KI/KO Gene : Txlna
    • Research Application : Inflammation An
    • Nomenclature : C57BL/6Smoc-Txl
    • Description : A Luciferase-2A
  • Tnf-IRES-NanoLuc

    Tnf-IRES-NanoLuc

    • Strain : Embryo cryopres
    • KI/KO Gene : Tnf
    • Research Application : Inflammation An
    • Nomenclature : C57BL/6Smoc-Tnf
    • Description : A IRES-NanoLuc
  • hPCSK9/hANGPTL3(4)

    hPCSK9/hANGPTL3(4)

    • Nomenclature : C57BL/6JSmoc-Pc
    • KI/KO Gene : Pcsk9
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : AI415265, AI747
  • hPD-1/hPVRIG

    hPD-1/hPVRIG

    • Nomenclature : C57BL/6JSmoc-Pd
    • KI/KO Gene : Pdcd1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : PD-1, Pdc1, Ly1
  • hPDGFRB

    hPDGFRB

    • Nomenclature : C57BL/6JSmoc-Pd
    • KI/KO Gene : Pdgfrb
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Pdgfr, CD140b,
  • hRAMP2

    hRAMP2

    • Nomenclature : C57BL/6JSmoc-Ra
    • KI/KO Gene : Ramp2
    • Strain : Developing
    • Description : Model Descripti
  • hIL3-hCSF2-Tg(NMG)

    hIL3-hCSF2-Tg(NMG)

    • Strain : Sperm cryoprese
    • Research Application : Immunodeficient
    • Nomenclature : NOD-PrkdcscidIl
    • KI/KO Gene : IL3
    • Description : These transgeni
  • hICOS(BALB/c)

    hICOS(BALB/c)

    • Strain : Developing
    • KI/KO Gene : ICOS
    • Research Application : Immunotherapy
    • Nomenclature : BALB/cAnSmoc-Ic
    • Description : The endogenous
  • hGPRC5D(2)

    hGPRC5D(2)

    • Nomenclature : BALB/cAnSmoc-Gp
    • KI/KO Gene : Gprc5d
    • Strain : Developing
    • Description : Model Descripti
  • hIGHE

    hIGHE

    • Nomenclature : C57BL/6JSmoc-Ig
    • KI/KO Gene : Ighe
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Gm900
  • hIL12RB1(2)

    hIL12RB1(2)

    • Nomenclature : C57BL/6JSmoc-Il
    • KI/KO Gene : Il12rb1
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : CD212, IL-12R(b
  • hIL1RL1/hIL4/hIL4R

    hIL1RL1/hIL4/hIL4R

    • Nomenclature : C57BL/6JSmoc-Il
    • KI/KO Gene : IL4Ra
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : Il4r, CD124
  • hIL22

    hIL22

    • Nomenclature : C57BL/6JSmoc-Il
    • KI/KO Gene : Il22
    • Strain : Repository Live
    • Description : Model Descripti
    • Synonyms : IL-22, Iltif, I
  • hIL4/hIL4R/hTSLP

    hIL4/hIL4R/hTSLP

    • Nomenclature : C57BL/6JSmoc-Il
    • KI/KO Gene : TSLP
    • Strain : Developing
    • Description : Model Descripti
  • hCLEC14A

    hCLEC14A

    • Nomenclature : C57BL/6JSmoc-Cl
    • KI/KO Gene : Clec14a
    • Strain : Developing
    • Description : Model Descripti
    • Synonyms : 1200003C23Rik