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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • hTIM4

    hTIM4

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ti
    • Strain : Repository Live
    • KI/KO Gene : Timd4
    • Synonyms : Tim4, TIM-4, B4
  • hTNFRSF1A

    hTNFRSF1A

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Embryo cryopres
    • Target : Cytokine Recept
    • KI/KO Gene : Tnfrsf1a
  • hTNFRSF12A

    hTNFRSF12A

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Tnfrsf12a
  • hTNFRSF10B

    hTNFRSF10B

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Embryo cryopres
    • Target : Cytokine Recept
    • KI/KO Gene : Tnfrsf10b
  • hTNC

    hTNC

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Developing
    • Target : Cytokine Recept
    • KI/KO Gene : Tnc
  • hTNFSF13B

    hTNFSF13B

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Developing
    • Target : Cytokines
    • KI/KO Gene : Tnfsf13b
  • hTNFRSF25

    hTNFRSF25

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tn
    • Strain : Embryo cryopres
    • Target : Cytokines
    • KI/KO Gene : Tnfrsf25
  • hTREM2

    hTREM2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tr
    • Strain : Repository Live
    • Target : Immune Checkpoi
    • KI/KO Gene : Trem2
  • Apoe-KO(SD)

    Apoe-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Apoeem1Smoc
    • Exon : Exon 2-4
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • Alb-2A-CreERT2(SD)

    Alb-2A-CreERT2(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Albem1(2A-Cr
    • Exon : Exon 2-4
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • Abcb11-KO(SD)

    Abcb11-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Abcb11em1Smo
    • Exon : Exon 4-6
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • Camk2a-IRES-Cre(SD)

    Camk2a-IRES-Cre(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Camk2aem1(IR
    • Exon : Exon 4-6
    • Strain : Developing
    • Target : Immune Checkpoi
  • Cacna1c-KO(SD)

    Cacna1c-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Cacna1cem1Sm
    • Exon : Exon 4
    • Strain : Developing
    • Target : Immune Checkpoi
  • Disc1-KO(SD)

    Disc1-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Disc1em1Smoc
    • Exon : Exon 2
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • Ldlr-KO(SD)

    Ldlr-KO(SD)

    • Description : Model Descripti
    • Nomenclature : SD-Ldlrem3Smoc
    • Exon : Exon 4
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • Axin2-2A-DreERT2

    Axin2-2A-DreERT2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ax
    • Exon : Exon 4
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • Atrn-2A-Cre

    Atrn-2A-Cre

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-At
    • Exon : Exon 4
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • hFCGR2B/h4-1BB(2)

    hFCGR2B/h4-1BB(2)

    • Description : hFCGR2B(NM-HU-2
    • Nomenclature : C57BL/6Smoc-Fcg
    • Exon : Exon 4
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • hGDF15

    hGDF15

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Gdf
    • Exon : Exon 4
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • hHER3

    hHER3

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Erb
    • Exon : Exon 4
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • hHER2

    hHER2

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Erb
    • Exon : Exon 4
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • hHBB

    hHBB

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Hbb
    • Exon : Exon 4
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • hICOS(2)

    hICOS(2)

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Ico
    • Exon : Exon 4
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi
  • hIGHG4

    hIGHG4

    • Description : The endogenous
    • Nomenclature : C57BL/6Smoc-Igh
    • Exon : Exon 4
    • Strain : Repository Live
    • Target : Immune Checkpoi
  • hIFNGR1/hIFNGR2

    hIFNGR1/hIFNGR2

    • Description : hIFNGR1(NM-HU-1
    • Nomenclature : C57BL/6Smoc-Ifn
    • Exon : Exon 4
    • Strain : Embryo cryopres
    • Target : Immune Checkpoi