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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • Il7-Luc-2A-EGFP

    Il7-Luc-2A-EGFP

    • Description : A Luciferase-2a
    • Nomenclature : C57BL/6Smoc-Il7
    • Strain : Embryo cryopres
    • KI/KO Gene : Il7
    • Synonyms : A630026I06Rik h
  • Il6-Luc-2A-EGFP

    Il6-Luc-2A-EGFP

    • Description : A Luciferase-2A
    • Nomenclature : C57BL/6Smoc-Il6
    • Strain : Embryo cryopres
    • KI/KO Gene : Il6
    • Synonyms : Il-6
  • MHCII/B2m-KO(NMG)

    MHCII/B2m-KO(NMG)

    • Description : All sequences f
    • Nomenclature : NOD.Cg-Prkdcsci
    • Strain : Repository Live
    • KI/KO Gene : B2M
    • Synonyms : y-m11; beta2m;
  • Prkdc/Il2rg-KO(NOD)

    Prkdc/Il2rg-KO(NOD)

    • Description : Prkdc and Il2rg
    • Nomenclature : NOD-Prkdcem1 Il
    • Strain : Embryo cryopres
    • KI/KO Gene : B2M
    • Synonyms : DNPK1 DOXNPH HY
  • Rag1-KO

    Rag1-KO

    • Description : Exon 2 of Rag1
    • Nomenclature : C57BL/6Smoc-Rag
    • Strain : Developing
    • KI/KO Gene : Rag1
    • Synonyms : Rag-1
  • R26-pAPOE-hCYP3A4(FVB)

    R26-pAPOE-hCYP3A4(FVB)

    • Description : This knock-in m
    • Nomenclature : FVB-Gt(ROSA)26S
    • Strain : Embryo cryopres
    • KI/KO Gene : Gt(ROSA)26Sor
    • Synonyms : R26,ROSA26,AV25
  • Siglec1-DTR-2A-tdTomato

    Siglec1-DTR-2A-tdTomato

    • Description : DTR-2A-tdTomato
    • Nomenclature : C57BL/6Smoc-Sig
    • Strain : Repository Live
    • KI/KO Gene : Tlr5
    • Synonyms : R26,ROSA26,AV25
  • hCXCL10

    hCXCL10

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cx
    • Strain : Developing
    • KI/KO Gene : Cxcl10
    • Synonyms : C7, IP10, CRG-2
  • hCTLA-4/hCD28(BALB/c)

    hCTLA-4/hCD28(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Ct
    • Strain : Embryo cryopres
    • KI/KO Gene : CD28
    • Synonyms : C7, IP10, CRG-2
  • hF3

    hF3

    hF3

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-F3
    • Strain : Developing
    • KI/KO Gene : F3
    • Synonyms : TF, Cf3, Cf-3,
  • hFCGR-Tg

    hFCGR-Tg

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Tg
    • Strain : Developing
    • KI/KO Gene : FCGR2A
    • Synonyms : CD32, FCG2, FcG
  • hGPNMB

    hGPNMB

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gp
    • Strain : Developing
    • KI/KO Gene : Gpnmb
    • Synonyms : DC-HIL,Dchil,ip
  • hGFRAL(BALB/c)

    hGFRAL(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Gf
    • Strain : Developing
    • KI/KO Gene : Gfral
    • Synonyms : Gral, AY457637
  • hGUCY2C

    hGUCY2C

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gu
    • Strain : Developing
    • KI/KO Gene : Gucy2c
    • Synonyms : Gcc, GC-C, AI89
  • hICAM1

    hICAM1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ic
    • Strain : Developing
    • KI/KO Gene : Icam1
    • Synonyms : CD54, Ly-47, Ic
  • hIGF1

    hIGF1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ig
    • Strain : Developing
    • KI/KO Gene : Igf1
    • Synonyms : Igf-1, Igf-I, C
  • hIGF2

    hIGF2

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ig
    • Strain : Developing
    • KI/KO Gene : Igf2
    • Synonyms : Mpr, M6pr, Peg2
  • hIL15RA(2)

    hIL15RA(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Strain : Developing
    • KI/KO Gene : Il15ra
    • Synonyms : IL-15RA, AA6901
  • hIL17RB

    hIL17RB

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Strain : Developing
    • KI/KO Gene : Il17rb
    • Synonyms : Evi27, Il17br,
  • hIL3/hCSF2(BALB/c)

    hIL3/hCSF2(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Il
    • Strain : Embryo cryopres
    • KI/KO Gene : IL3
    • Synonyms : BPA, PSF, HCG
  • hCD19(BALB/c)

    hCD19(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Cd
    • Strain : Developing
    • KI/KO Gene : Cd19
    • Synonyms : AW495831
  • hCD28/hPD-1/hPD-L1

    hCD28/hPD-1/hPD-L1

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Developing
    • KI/KO Gene : CD28
    • Synonyms : AW495831
  • hCD27/hPD-1(BALB/c)

    hCD27/hPD-1(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Cd
    • Strain : Developing
    • KI/KO Gene : CD27
    • Synonyms : Cd27, S152, T
  • hCD79A/hCD79B

    hCD79A/hCD79B

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Embryo cryopres
    • KI/KO Gene : CD79a
    • Synonyms : Iga, Ly54, mb
  • hCD79A

    hCD79A

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Cd
    • Strain : Embryo cryopres
    • KI/KO Gene : Cd79a
    • Synonyms : Iga, Ly54, mb-1