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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • Gadd45gip1-Flox

    Gadd45gip1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ga
    • Exon : Exon s
    • Disease : Type 2 Diabetes
    • KI/KO Gene : Gadd45gip1
  • G6pc-KO

    G6pc-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-G6
    • Exon : Exon 3
    • Disease : glycogen storag
    • KI/KO Gene : G6pc
  • Glul-Flox

    Glul-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gl
    • Exon : Exon 4-7
    • Disease : Temporal Lobe E
    • KI/KO Gene : Glul
  • Gla-KO

    Gla-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gl
    • Exon : Exon 2-3
    • Application : Fabry Disease R
    • Disease : Fabry Disease
  • Gucy2c-KO

    Gucy2c-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gu
    • Exon : Exon 3
    • Application : Therapeutic Ant
    • Disease : Obesity
  • Ins2-C96Y

    Ins2-C96Y

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-In
    • Exon : Exon 3
    • Application : Diabetes Relate
    • Disease : Diabetes
  • Il33-KO(3)

    Il33-KO(3)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Exon : Exon 2.
    • Application : Diabetes Relate
    • Disease : Alzheimer's dis
  • Il33-KO(2)

    Il33-KO(2)

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Il
    • Exon : Exon 3-7.
    • Application : Immune
    • Disease : Alzheimer's dis
  • Il10-KO(BALB/c)

    Il10-KO(BALB/c)

    • Description : Model Descripti
    • Nomenclature : BALB/cAnSmoc-Il
    • Exon : Exon 1-5
    • Application : Research On Erk
    • Disease : Inflammatory Bo
  • kif18A-KO

    kif18A-KO

    • Description : Model Descripti
    • Nomenclature : B6;129S-kif18At
    • Exon : Exon 2
    • Application : Male Infertilit
    • Disease : Inflammatory Bo
  • Jakmip1-KO

    Jakmip1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ja
    • Exon : Exon 4-8
    • Application : Male Infertilit
    • Disease : Autism Spectrum
  • Irs1-KO

    Irs1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ir
    • Exon : Exon 1
    • Application : Diabetes Relate
    • Disease : Type 2 Diabetes
  • Lrrc10-KO

    Lrrc10-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lr
    • Exon : Exon 1
    • Application : Diabetes Relate
    • Disease : Dilated Cardiom
  • Mus81-KO

    Mus81-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mu
    • Exon : Exon 1-10
    • Application : Research On Hom
    • Disease : Marfan Syndrome
  • Mefv-hMEFV*V726A

    Mefv-hMEFV*V726A

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon 7-10
    • Application : Familial Medite
    • Disease : Familial Medite
  • Nos1-KO

    Nos1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-No
    • Exon : Exon 3
    • Application : Familial Medite
    • Disease : Hypertrophic Ca
  • Nf2-Flox

    Nf2-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nf
    • Exon : Exon 2
    • Application : Cancer Research
    • Disease : Renal Cell Carc
  • Nexn-Flox

    Nexn-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ne
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Dilated Cardiom
  • Neil1-KO

    Neil1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ne
    • Exon : Exon 2-3
    • Application : Cancer Research
    • Disease : Abdominal Obesi
  • Ncoa6-Flox

    Ncoa6-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nc
    • Exon : Exon s
    • Application : Cancer Research
    • Disease : Dilated Cardiom
  • Park7-KO

    Park7-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pa
    • Exon : Exon 3-5
    • Application : A Sensor For Ox
    • Disease : Parkinson's Dis
  • Otc-KO

    Otc-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ot
    • Exon : Exon 2
    • Application : Research On Cdk
    • Disease : Ornithine Carba
  • Pianp-KO

    Pianp-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pi
    • Exon : Exon 3
    • Application : Research On Cdk
    • Disease : Autism Spectrum
  • Pdlim5-KO

    Pdlim5-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pd
    • Exon : Exon 3
    • Application : Research On Cdk
    • Disease : dilated cardiom
  • Pomc-KO

    Pomc-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pd
    • Exon : Exon 2-3
    • Application : Early Onset Obe
    • Disease : Obesity