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Animal Model

Shanghai Model Organisms Center, Inc.

Animal Model

Animal models play a crucial role in scientific research and are widely used to study various aspects of biology, medicine, and behavior. These models involve the use of animals, such as mice, rats, rabbits, and primates, to mimic human physiology and understand disease mechanisms, develop new treatments, and test the safety and efficacy of drugs. Animal models provide a controlled experimental environment that allows researchers to investigate complex biological processes in a living system. By selectively breeding animals or using genetic modification techniques, scientists can create models that exhibit specific traits or conditions relevant to human diseases. For instance, mice with a specific gene mutation can be used to study the genetic basis of cancer or neurodegenerative disorders.

  • H11-CAG-LSL-Myc

    H11-CAG-LSL-Myc

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ig
    • Application : Tumor-Bearing M
    • KI/KO Gene : Igs2
    • Synonyms : H11,Hipp11,Iis2
  • Inppl1-KO

    Inppl1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-In
    • Exon : Exon 5
    • Application : Cancer Related;
    • Disease : Type 2 Diabetes
  • Ifng-KO

    Ifng-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-If
    • Exon : Exon 1-4.
    • Application : Cancer Related;
    • Disease : Malaria
  • Lrp1-Flox

    Lrp1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lr
    • Exon : Exon  7-8 of
    • Application : Cancer Related;
    • Disease : Cardiomyopathy
  • Lrfn2-KO

    Lrfn2-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Lr
    • Exon : Exon 2
    • Application : Cancer Related;
    • Disease : Autism Spectrum
  • Mdk-KO

    Mdk-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Md
    • Exon : Exon 3-4
    • Application : Therapeutic Ant
    • Disease : Schizophrenia
  • Mc3r-KO

    Mc3r-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Mc
    • Exon : Exon 1
    • Application : Obesity
    • Disease : Obesity
  • Mybpc3-KO

    Mybpc3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-My
    • Exon : Exon 3-5
    • Application : Obesity
    • Disease : Hypertrophic Ca
  • Med1-Flox

    Med1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Me
    • Exon : Exon s
    • Application : Obesity
    • Disease : Dilated Cardiom
  • Nr5a1-Flox

    Nr5a1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Nr
    • Exon : Exon 4
    • Application : Research On Gen
    • Disease : Hypogonadotropi
  • Npy1r-KO

    Npy1r-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Np
    • Exon : Exon 2
    • Application : Endocrine And M
    • Disease : Obesity
  • Nos3-KO

    Nos3-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-No
    • Exon : Exon 10-11
    • Application : Endocrine And M
    • Disease : Hypertrophic Ca
  • Pdgfrb-Flox

    Pdgfrb-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pd
    • Exon : Exon 3-7
    • Application : Ret Signal Tran
    • Disease : Autism Spectrum
  • Plcb1-KO

    Plcb1-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pl
    • Exon : Exon 7
    • Application : Ret Signal Tran
    • Disease : Alzheimer's dis
  • Prkn-KO

    Prkn-KO

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Pr
    • Exon : Exon 3.
    • Application : Immune-Related
    • Disease : Parkinson's Dis
  • R26-CAG-LSL-hFGFR2*S320C-IRES-Luc-2A-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 3.
    • Application : Cancer Research
    • Disease : Parkinson's Dis
  • R26-CAG-LSL-hEML4/ALK-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 3.
    • Application : Cancer Research
    • Disease : Parkinson's Dis
  • R26-CAG-LSL-hEGFR*T790M/del19-Luc-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 3.
    • Application : Cancer
    • Disease : Parkinson's Dis
  • R26-CAG-LSL-hEGFR*T790M-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 3.
    • Application : Cancer Research
    • Disease : Parkinson's Dis
  • R26-CAG-LSL-hIDH2*R140Q-IRES-Luc-2A-tdTomato

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 3.
    • Application : Cancer Research
    • Disease : D-2-Hydroxyglut
  • R26-CAG-LSL-hHER2*ex20ins-IRES-Luc-2A-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 20
    • Application : Cancer Research
    • Disease : D-2-Hydroxyglut
  • R26-CAG-LSL-hTM6SF2*E167K-EGFP

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Gt
    • Exon : Exon 20
    • Application : Non-Alcoholic F
    • Disease : D-2-Hydroxyglut
  • Senp1-Flox

    Senp1-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Se
    • Exon : Exon 4
    • Application : Non-Alcoholic F
    • Disease : Type 1 Diabetes
  • Rrn3-Flox

    Rrn3-Flox

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Rr
    • Exon : Exon s
    • Application : Non-Alcoholic F
    • Disease : Parkinson's Dis
  • Raf1-D486N

    Raf1-D486N

    • Description : Model Descripti
    • Nomenclature : C57BL/6JSmoc-Ra
    • Exon : Exon s
    • Application : Noonan Syndrome
    • Disease : Parkinson's Dis