TPU-0037C is a metabolite of the marine actinomycete S. platensis that is structurally similar to lydicamycin . It is active against Gram-positive bacteria (MICs = 0.39-3.13 ug/ml), including methicillin-resistant S. aureus strains (MIC = 3.13 ug/ml), but is ineffective against Gram-negative bacteria (MICs = >50 ug/ml).