Thiocarlide

Mfr.No.	T38073
Description	Thiocarlide (isoxyl) is a thiourea derivative that was used in the 1960s to successfully treat tuberculosis (TB). It has considerable antimycobacterial activity in vitro and is effective against multi-drug resistant strains of Mycobacterium tuberculosis in the range of 1-10 &#181g/ml. (1) (2) At concentrations of 10 &#181M, isoxyl inhibits the synthesis of M. bovis during six hours of exposure which is similar to isoniazid (INH) and ethionamide (ETH), two other predominant anti-tuberculosis drugs. Unlike INH and ETH, isoxyl also partially inhibits the synthesis of fatty acids. Isoxyl shows no acute toxicity against primary macrophage cell cultures as demonstrated by diminution of redox activity.(2)
Alternative Names	Isoxyl
Molecular Formula	C23H32N2O2S
Signaling Pathways	Others
Smiles	CC(C)CCOc1ccc(NC(=S)Nc2ccc(OCCC(C)C)cc2)cc1
Cas Number	910-86-1
Molecular Weight	400.58
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20427089	T38073	1 g	$940	Add to Cart
BHB20427089	T38073	50 mg	$73	Add to Cart
BHB20427089	T38073	100 mg	$135	Add to Cart
BHB20427089	T38073	500 mg	$540	Add to Cart