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TASP 0277308

SKU : BHB20428880

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Description
Review(s)

Mfr.No.	T41145
Description	TASP 0277308 is a potent and selective sphingosine 1-phosphate 1 (S1P1) receptor antagonist (IC50 = 7.8 nM). TASP 0277308 inhibits S1P-induced chemotaxis (IC50 = 1.1-1.6 nM), HUVEC cell proliferation (IC50 = 3-3.6 nM) and suppresses angiogenesisin vivo. TASP 0277308 also blocks VEGF-induced tube-formation of HUVECsin vitroand reverses or impairs the development of arthritis or mechano-allodynia.
Molecular Formula	C23H28Cl2N6O3S
Signaling Pathways	Others
Smiles	O(C=1N(CC)C((CH)(NS(=O)(=O)C2=CC(Cl)=C(Cl)C=C2)C)=NN1)C3=CC(=CC=C3)N4CCN(C)CC4
Cas Number	945725-50-8
Molecular Weight	539.48
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20428880	T41145	5 mg	$793		Add to Cart

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TASP 0277308

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