Sordarin sodium

Mfr.No.	T36434
Description	Sordarin is an inhibitor of fungal protein synthesis originally isolated from S. araneosa.(1) It binds to elongation factor 2 (EF-2) in the presence of ribosomes and inhibits the uncoupled GTPase activity of equimolar mixtures of EF-2 and ribosomes from C. albicans (IC50 = 0.1 uM). Sordarin inhibits protein synthesis in cell-free lysates of C. albicans, C. glabrata, and C. neoformans (IC50s = 0.01, 0.2, and 0.06 ug/ml, respectively) but not in rabbit reticulocytes (IC50 = >100 ug/ml).(1) (2) It inhibits the growth of C. albicans (MIC = 8 ug/ml) but not C. glabrata or C. neoformans (MICs = >125 ug/ml).
Alternative Names	Sordarin (sodium salt)
Molecular Formula	C27H40NaO8
Signaling Pathways	Others
Smiles	(Na).(H)(C)12C(C)3(C=O)(C)4((H))CC(CH)(C)(C)4((H))C(C)1(CO(CH)1O(CH)(C)(CH)(OC)(CH)(O)(CH)1O)(C)3(C(O)=O)C(=C2)C(C)C \|c:37,TLB:7:4:16:35.34,15:16:3.4:35.34,THB:5:4:16:35.34,35:2:30:7.13.15\|
Cas Number	463356-00-5
Molecular Weight	515.599
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20425728	T36434	5 mg	$1200		Add to Cart