Senicapoc

Mfr.No.	T3528
Description	Senicapoc (ICA-17043) is a potent inhibitor of the Gardos channel and ameliorates RBC dehydration in the SAD mouse. Senicapoc blocked Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ± 2 nM (CLT IC50 = 100 ± 12 nM) and inhibited RBC dehydration with an IC50 of 30 ± 20 nM. Senicapoc is in treatment of Sickle Cell Disease and Sickle Cell Anemia
Alternative Names	ICA-17043
Molecular Formula	C20H15F2NO
Signaling Pathways	Membrane transporter/Ion channel
Smiles	C(C(N)=O)(C1=CC=C(F)C=C1)(C2=CC=C(F)C=C2)C3=CC=CC=C3
Cas Number	289656-45-7
Molecular Weight	323.34
Target	Potassium Channel

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SKU	Supplier No.	Size	Your price
BHB20424743	T3528	1 mL	$65	Add to Cart
BHB20424743	T3528	5 mg	$54	Add to Cart
BHB20424743	T3528	10 mg	$87	Add to Cart
BHB20424743	T3528	25 mg	$135	Add to Cart
BHB20424743	T3528	50 mg	$177	Add to Cart
BHB20424743	T3528	100 mg	$237	Add to Cart
BHB20424743	T3528	200 mg	$353	Add to Cart