RCTR1

Mfr.No.	T37166
Description	Resolvin conjugate in tissue regeneration 1 (RCTR1) is a specialized pro-resolving mediator (SPM) biosynthesized from docosahexaenoic acid by isolated human macrophages and apoptotic polymorphonuclear (PMN) neutrophils.1It has been found in human spleen and bone marrow.2RCTR1 is produced via lipoxygenase-mediated oxidation of DHA to 7(S)-8-epoxy-17(S)-HDHA, which is conjugated to glutathione.1,2,3RCTR1 (10 nM) increases phagocytosis ofE. colior apoptotic neutrophils in isolated human monocyte-derived macrophages.2It decreases chemotaxis induced by leukotriene B4in isolated human neutrophils when used at a concentration of 10 nM. RCTR1 (1 and 10 nM) accelerates tissue regeneration in planaria. Intraperitoneal administration of RCTR1 (100 ng/animal) shortens the inflammatory resolution period and decreases inflammatory exudate neutrophil infiltration in a mouse model ofE. coli-induced peritonitis.
Molecular Formula	C32H47N3O10S
Signaling Pathways	Others
Smiles	CCC=C/C(CH)(O)C=CC=C/C=C/C=C/(CH)(SC(CH)(NC(=O)CC(CH)(N)C(O)=O)C(=O)NCC(O)=O)(CH)(O)CC=C/CCC(O)=O
Cas Number	2095607-49-9
Molecular Weight	665.8
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20426358	T37166	10 ?g	$497	Add to Cart
BHB20426358	T37166	25 ?g	$1140	Add to Cart
BHB20426358	T37166	50 ?g	$2150	Add to Cart