rac-trans-4-hydroxy Glyburide

Mfr.No.	T35635
Description	rac-trans-4-hydroxy Glyburide is an active metabolite of the SUR1/Kir6.2 sulfonylurea inhibitor glyburide .1,2It is formed from glyburide by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9.1rac-trans-4-hydroxy Glyburide inhibits glyburide binding to rat brain synaptosomes at the high and low affinity sites of SUR1/Kir6.2 with IC50values of 0.95 and 100 nM, respectively.2
Molecular Formula	C23H28ClN3O6S
Signaling Pathways	Others
Smiles	COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)N(CH)1CC(CH)(O)CC1 \|wU:27.28,wD:30.32,(-4,-25.41,;-4,-23.87,;-5.33,-23.1,;-6.67,-23.87,;-8,-23.1,;-8,-21.56,;-9.34,-20.79,;-6.67,-20.79,;-5.33,-21.56,;-4,-20.79,;-2.67,-21.56,;-4,-19.25,;-2.67,-18.48,;-2.67,-16.94,;-1.33,-16.17,;-1.33,-14.63,;,-13.86,;1.33,-14.63,;1.33,-16.17,;,-16.94,;2.67,-13.86,;1.9,-12.53,;3.44,-15.19,;4,-13.09,;5.33,-13.86,;5.33,-15.4,;6.67,-13.09,;8,-13.86,;9.34,-13.09,;10.67,-13.86,;10.67,-15.4,;12,-16.17,;9.34,-16.17,;8,-15.4,)\|
Cas Number	23155-00-2
Molecular Weight	510
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20425044	T35635	1 mg	$288		Add to Cart