PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)

Mfr.No.	T36939
Description	The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, also known as PIP3, is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. PIP3 can serve as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains. Protein binding to PIP3 is important for cytoskeletal rearrangement and membrane trafficking. PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) is a synthetic analog of natural PIP3 with C6:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as that of the natural compound. The short fatty acid chains of this analog give it different physical properties from naturally-occurring PIP3, including higher solubility in aqueous media.
Molecular Formula	C21H45NO22P4
Signaling Pathways	Others
Smiles	N.CCCCCC(=O)OC(CH)(COP(O)(=O)O(CH)1(CH)(O)(CH)(OP(O)(O)=O)(CH)(OP(O)(O)=O)(CH)(OP(O)(O)=O)(CH)1O)OC(=O)CCCCC
Cas Number	799268-62-5
Molecular Weight	787.471
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20426157	T36939	1 mg	$973	Add to Cart
BHB20426157	T36939	100 ?g	$125	Add to Cart
BHB20426157	T36939	500 ?g	$550	Add to Cart