PLX8394

Mfr.No.	T3579
Description	PLX8394 is an orally active inhibitor of serine/threonine-protein kinase B-Raf (BRAF) protein. PLX8394 can selectively bind to and inhibit the activity of both wild-type and mutated forms of BRAF, then inhibit the proliferation of tumor cells which express mutated forms of BRAF. PLX8394 appears to be effective against tumors that express multiple mutated forms of the kinase and may be an effective therapeutic agent for tumors that are resistant to other BRAF inhibitor therapies that are specific for the BRAF V600E mutant.
Molecular Formula	C25H21F3N6O3S
Signaling Pathways	MAPK
Smiles	C(=O)(C=1C=2C(NC1)=NC=C(C2)C=3C=NC(=NC3)C4CC4)C5=C(F)C(NS(=O)(=O)N6CC(CH)(F)C6)=CC=C5F
Cas Number	1393466-87-9
Molecular Weight	542.53
Target	Raf

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SKU	Supplier No.	Size	Your price
BHB20425175	T3579	1 mL	$123	Add to Cart
BHB20425175	T3579	1 mg	$44	Add to Cart
BHB20425175	T3579	2 mg	$54	Add to Cart
BHB20425175	T3579	5 mg	$91	Add to Cart
BHB20425175	T3579	10 mg	$143	Add to Cart
BHB20425175	T3579	25 mg	$258	Add to Cart
BHB20425175	T3579	50 mg	$383	Add to Cart
BHB20425175	T3579	100 mg	$559	Add to Cart