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Pexidartinib hydrochloride

SKU : BHB20432898

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Description
Review(s)

Mfr.No.	T62788
Description	Pexidartinib hydrochloride (PLX-3397 hydrochloride) is a potent, selective, orally active, ATP-competitive inhibitor of colony-stimulating factor 1 (CSF1R or M-CSFR) (IC50: 20 nM) and c-Kit (IC50: 10 nM). Pexidartinib hydrochloride is 10-100 times more selective for c-Kit and CSF1R than for other related kinases, acting on FLT3 (IC50: 160 nM), KDR (VEGFR2) (IC50: 350 nM), LCK (IC50: 860 nM), FLT1 (VEGFR1) (Pexidartinib hydrochloride induces apoptosis and exhibits anti-tumour effects.
Molecular Formula	C20H16Cl2F3N5
Signaling Pathways	Others
Smiles	Cl.FC(F)(F)c1ccc(CNc2ccc(Cc3c(nH)c4ncc(Cl)cc34)cn2)cn1
Cas Number	2040295-03-0
Molecular Weight	454.28
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20432898	T62788	2 mg	$30		Add to Cart

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Pexidartinib hydrochloride

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