OTS514

Mfr.No.	T4134L
Description	OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell lines (IC50: 0.4 ~ 42.6 nM). Treatment with OTS514 suppressed forkhead box protein M1 (FOXM1) activity. OTS514 treatment reduced CD90-positive SCLC cells and showed a higher cytotoxic effect against lung sphere-derived CSC-like SCLC cells.
Alternative Names	OTS514
Molecular Formula	C21H20N2O2S
Signaling Pathways	MAPK, Apoptosis
Smiles	OC=1C(=C2C3=C(C(=O)NC2=C(C)C1)SC=C3)C4=CC=C((CH)(CN)C)C=C4
Cas Number	1338540-63-8
Molecular Weight	364.46
Target	Apoptosis, TOPK

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SKU	Supplier No.	Size	Your price
BHB20428995	T4134L	1 mL	$169	Add to Cart
BHB20428995	T4134L	2 mg	$89	Add to Cart
BHB20428995	T4134L	5 mg	$155	Add to Cart
BHB20428995	T4134L	10 mg	$269	Add to Cart