Neoaureothin

Mfr.No.	T35668
Description	Neoaureothin is a bacterial metabolite that has been found in Streptomyces. It is an androgen receptor (AR) antagonist that inhibits binding of dihydrotestosterone (DHT) to ARs (IC50 = 13 uM) and inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells (IC50 = 1.75 nM). Neoaureothin is cytotoxic to A549, HCT116, and HepG2 cells (IC50s = 34.3, 47, and 37.2 ug/ml, respectively). It also has nematocidal activity against the pine wood nematode B. xylophilus (LC50 = 0.84 ug/ml) and increases survival of P. densiflora trees inoculated with B. xylophilus.
Molecular Formula	C28H31NO6
Signaling Pathways	Others
Smiles	COc1oc((CH)2CC(CO2)=CC(C)=CC(C)=CC(C)=Cc2ccc(cc2)N(=O)=O)c(C)c(=O)c1C
Cas Number	59795-94-7
Molecular Weight	477.557
Target	Others

Have you used this product?

SKU	Supplier No.	Size	Your price	Quantity
BHB20425076	T35668	2500 ?g	$2660		Add to Cart